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Table 4 Excess cardiovascular event (CVE) risk due to prevalent diabetes mellitus (DM) at baseline and incident DM during follow-up

From: Prognostic value of long-term trajectories of depression for incident diabetes mellitus in patients with stable coronary heart disease

 

Hazard ratio (95 %-CI)

Prevalent DM vs.

no prevalent DMa

Prevalent + incident DM

vs. no DM

Incident DM

vs. no DMb

NCVE/NTotal

296/1048

296/1048

219/831

Age- and sex-adjusted models

Class 1 (low-stable)

1.40 (1.03, 1.90)

1.39 (1.05, 1.85)

1.31 (0.82, 2.11)

Class 2 (moderate-stable)

1.51 (0.97, 2.36)

1.18 (0.79, 1.78)

0.76 (0.41, 1.39)

Class 3 (increasing)

0.66 (0.31, 1.42)

0.71 (0.38, 1.33)

0.80 (0.32, 1.97)

Class 4 (high-stable)

1.68 (0.75, 3.80)

4.65 (1.95, 11.1)

6.59 (2.69, 16.1)

Fully adjusted modelsc

Class 1 (low-stable)

1.31 (0.95, 1.79)

1.31 (0.98, 1.75)

1.26 (0.77, 2.05)

Class 2 (moderate-stable)

1.45 (0.69, 2.27)

1.11 (0.74, 1.67)

0.72 (0.39, 1.33)

Class 3 (increasing)

0.66 (0.31, 1.40)

0.69 (0.37, 1.29)

0.78 (0.32, 1.86)

Class 4 (high-stable)

1.73 (0.78, 3.86)

4.66 (1.98, 10.9)

6.51 (2.77, 15.3)

  1. a Ignoring incident DM during follow-up
  2. b Excluding patients with prevalent DM at baseline
  3. c Adjusted for age, sex, education, smoking status, BMI, and physical activity