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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double‐blind placebo‐controlled clinical trials

Fig. 1

Changes in glucose metabolism markers from baseline to Week 12 (LOCF). * p < 0.05, ** p < 0.01, *** p < 0.001 vs. placebo (ANCOVA with baseline value as covariate). HOMA-IR was calculated using the following formula: HOMA-IR = fasting serum insulin (µU/mL) × fasting plasma glucose (mmol/L)/22.5. HOMA-IR homeostatic model assessment of insulin resistance, HbA1c hemoglobin A1c, SD standard deviation, LS least squares, CI confidence interval, LOCF last observation carried forward, ANCOVA analysis of covariance

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