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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Expression of the SARS-CoV-2 receptorACE2 in human heart is associated with uncontrolled diabetes, obesity, and activation of the renin angiotensin system

Fig. 1

ACE2 mRNA is highly expressed in cardiac atrial biopsies and increased in cardiac biopsies of diabetic patients. a ACE2 mRNA expression is increased in human diabetic cardiac biopsies vs non-diabetic patients. *p = 0.02. b ACE2 mRNA expression is not significantly different between human cardiac biopsies of patients on ACEi, ARBs or no RAS blockers prior to the CABG operation. c ACE2 mRNA expression is not significantly different between hypertrophic heart vs no hypertrophic heart. d ACE2 mRNA expression in the human cardiac biopsies is positively correlated with HbA1c. e ACE2 mRNA expression in human cardiac biopsies is inversely correlated with fractional shortening (FS). f ACE2 mRNA expression in the human cardiac biopsies is positively correlated with BMI measured kg/m2 as measured prior to the operation. g There was no correlation between patients' age and ACE2 mRNA expression in the cardiac biopsies. RPLPO gene was used as the internal control. Values are shown as mean ± SEM. P value evaluated with paired Student’s t-test, *p < 0.05

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Cardiovascular Diabetology

ISSN: 1475-2840