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Table 4 Absolute difference in adjusted cumulative incidence of diabetes (95% CI)

From: Treatment with direct oral anticoagulants or warfarin and the risk for incident diabetes among patients with atrial fibrillation: a population‐based cohort study

 

6 months

12 months

18 months

24 months

DOACs vs Warfarin (ref.)

 Apixaban vs Warfarin

− 0.79 (− 1.55 to 0.06)

− 1.21 (− 2.44 to 0.09)

− 1.66 (− 3.34 to 0.13)

− 2.06 (-4.08 to 0.16)

 Dabigatran vs Warfarin

− 1.17 (− 1.86 to − 0.41)

− 1.80 (− 2.86 to − 0.65)

− 2.47 (− 3.93 to − 0.92)

− 3.06 (− 4.79 to − 1.15)

 Rivaroxaban vs Warfarin

− 0.69 (− 1.42 to 0.09)

− 1.06 (− 2.14 to 0.13)

− 1.46 (− 2.93 to 0.19)

− 1.80 (− 3.62 to 0.23)

 Apixaban/ Rivaroxaban vs Warfarin

− 0.74 (− 1.39 to − 0.05)

− 1.14 (− 2.10 to − 0.08)

− 1.56 (− 2.83 to − 0.11)

− 1.93 (− 3.62 to − 0.14)

DOACs vs DOACs (ref.)

 Apixaban vs Dabigatran

0.38 (− 0.38 to 1.13)

0.59 (− 0.59 to 1.69)

0.81 (− 0.79 to 2.34)

1.00 (− 0.97 to 2.86)

 Rivaroxaban vs Dabigatran

0.48 (− 0.20 to 1.11)

0.74 (− 0.31 to 1.73)

1.01 (− 0.43 to 2.31)

1.26 (− 0.52 to 2.86)

 Rivaroxaban vs Apixaban

0.10 (− 0.73 to 0.85)

0.15 (− 1.07 to 1.34)

0.21 (− 1.49 to 1.85)

0.26 (− 1.81 to 2.30)

 Apixaban/ Rivaroxaban vs Dabigatran

0.43 (− 0.14 to 0.93)

0.66 (− 0.22 to 1.42)

0.91 (− 0.31 to 2.00)

1.13 (− 0.38 to 2.47)

  1. 95% confidence interval was estimated using bootstrap methods