Table 1 Baseline characteristics and comorbidities in AF patients with and without DM
From: Prognostic significance of diabetes mellitus in patients with atrial fibrillation
Clinical characteristics | Total population (n = 1109) | AF with DM (n = 373) | AF without DM (n = 736) | P value (comparing DM vs no-DM) |
|---|---|---|---|---|
Gender | M: 603 F: 506 | M:196 F: 177 | M: 407 F: 329 | 0.350 |
Age (years) | 73.6 ± 10.9 | 75.2 ± 8.8 | 72.9 ± 11.7 | < 0.001 |
Body mass index (kg/m2) | 28.5 ± 5.4 | 29.5 ± 5.6 | 28.0 ± 5.4 | < 0.001 |
Glomerular filtration rate (GFR) by CKD-EPI (mL/min/1.73 m2) | 60.4 ± 23.6 | 57.0 ± 22.4 | 64.7 ± 23.6 | < 0.001 |
Left ventricular ejection fraction (%) | 49.2 ± 12.2 | 48.4 ± 12.3 | 49.7 ± 12.1 | 0.113 |
NT-pro-BNP | 2430.2 ± 5525.3 | 2331.5 ± 4991.1 | 2289.5 ± 5460.2 | 0.915 |
Glycated hemoglobin (%) | 6.52 ± 1.10 | 6.85 ± 1.14 | 5.77 ± 0.43* | < 0.001 |
Medical histories | N (%) | Â | Â | Â |
 Hypertension | 888 (80.1) | 317 (87.3) | 571 (78.0) | < 0.001 |
 Dyslipidemia | 527 (47.5) | 223 (61.4) | 304 (41.5) | < 0.001 |
 Chronic obstructive pulmonary disease | 142 (12.8) | 59 (16.2) | 83 (11.3) | 0.028 |
 Heart failure | 553 (49.9) | 213 (58.8) | 340 (46.5) | < 0.001 |
 Strokes | 164 (14.8) | 73 (20.1) | 91 (12.5) | 0.001 |
 Myocardial infarction | 228 (20.6) | 91 (25.1) | 137 (18.7) | 0.018 |
 Chronic kidney disease | 162 (14.6) | 84 (23.1) | 78 (10.7) | < 0.001 |
 Vascular disease | 509 (45.9) | 210 (57.9) | 299 (40.8) | < 0.001 |
Treatment and risk stratification scores | ||||
 Rhythm control treatment | 409 (36.9%) | 109 (29.2%) | 300 (40.7%) | 0.002 |
 Use of antiplatelet(s) at discharge | 218 (19.7%) | 97 (31.5%) | 121 (15.8%) | 0.002 |
Use of oral anticoagulant(s) at discharge: | Â | Â | Â | 0.672 |
Vitamin K antagonist | 282 (25.4%) | 101 (27.1%) | 181 (24.6%) | Â |
NOAC | 522 (47.1%) | 171 (45.8%) | 351 (47.7%) | Â |
HAS-BLED score at discharge | 1.7 ± 1 | 2 ± 1.1 | 1.7 ± 1 | < 0.001 |
CHA(2)DS(2)-VASc score at discharge | 4.4 ± 1.9 | 5.6 ± 1.6 | 3.8 ± 1.8 | < 0.001 |