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Table 3 Invasive pressure volume loop parameters

From: Load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction

 Sham + controlSham + empaMI + vehicleMI + empa
SBP (mmHg) 127 ± 4146 ± 3120 ± 4*132 ± 5
dP/dtmax7623 ± 3267903 ± 1836010 ± 2486292 ± 249
dP/dtmin− 7834 ± 417− 8234 ± 224− 4870 ± 251− 5248 ± 261
PRSW (mmHg)74 ± 380 ± 362 ± 5*75 ± 6
EDP (mmHg)11.1 ± 0.610.2 ± 0.616.0 ± 1*14 ± 1
Tau (msec)12.0 ± 0.512.1 ± 0.317.1 ± 0.5*16.5 ± 0.5
EDPVR (mmHg/s)0.029 ± 0.0020.026 ± 0.0020.046 ± 0.004*0.054 ± 0.005
  1. Data are expressed as mean ± SEM. N = 23–24 in sham + control and sham + empa groups; N = 19-23 in MI + vehicle and MI + empa groups
  2. SBP systolic blood pressure, EDP end-diastolic pressure, dP/dtmax maximum rate of pressure rise, dP/dtmin maximal rate of pressure decline, EDPVR end-diastolic pressure volume relationship
  3. * p < 0.05 vs. sham control group
  4. p < 0.05 vs. MI +vehicle group
  5. p = 0.056 c/w MI + vehicle