Table 1 Baseline characteristics of participants according to quartiles of TyG index
Characteristics | Overall | Quartiles of TyG index | P value | |||
|---|---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | |||
No. of participants | 98,849 | 24,712 | 24,716 | 24,708 | 24,713 | |
TyG index | 8.58 (8.18–9.06) | 7.91 (7.70–8.06) | 8.39 (8.29–8.48) | 8.79 (8.68–8.91) | 9.46 (9.23–9.82) | < 0.0001 |
Age, years | 51.81 (43.60–59.23) | 50.77 (41.81–58.91) | 51.82 (43.60–59.18) | 52.36 (44.22–59.70) | 52.16 (44.44–58.96) | < 0.0001 |
Men, n (%) | 78,835 (79.75) | 18,283 (73.98) | 19,634 (79.44) | 20,104 (81.37) | 20,814 (84.22) | < 0.0001 |
High school or above, n (%) | 19,189 (20.09) | 5781 (24.32) | 4586 (19.12) | 4561 (19.12) | 4261 (17.84) | < 0.0001 |
Income > 800 RMB/month, n (%) | 13,659 (14.31) | 3699 (15.57) | 3223 (13.45) | 3357 (14.08) | 3380 (14.16) | < 0.0001 |
Body mass index, kg/m2 | 24.84 (22.60–27.22) | 23.14 (21.11–25.34) | 24.44(22.39–26.64) | 25.43 (23.4–27.67) | 26.30 (24.22–28.41) | < 0.0001 |
Systolic blood pressure, mm Hg | 130.00 (119.30–141.30) | 120.00 (110.00–136.00) | 129.30 (117.30–140.00) | 130.00 (120.00–145.00) | 132.00 (120.00–150.00) | < 0.0001 |
Diastolic blood pressure, mm Hg | 80.00 (78.70–90.00) | 80.00 (70.70–85.00) | 80.00 (77.30–90.00) | 81.00 (79.30–90.00) | 85.00 (80.00–92.00) | < 0.0001 |
Current smoker, n (%) | 33,064 (34.34) | 8014 (33.50) | 7750 (32.10) | 8284 (34.39) | 9016 (37.37) | < 0.0001 |
Current alcohol use, n (%) | 35,945 (37.32) | 8941 (37.36) | 8415 (34.85) | 8921 (37.02) | 9668 (40.07) | < 0.0001 |
Active physical activity, n (%) | 87,005 (91.28) | 21,660 (91.33) | 21,964 (91.77) | 21,641 (90.85) | 21,740 (91.19) | 0.0046 |
Diabetes Mellitus, n (%) | 3033 (3.07) | 182 (0.74) | 348 (1.41) | 667 (2.70) | 1836 (7.43) | < 0.0001 |
Hypertension, n (%) | 12,300 (12.44) | 1899 (7.685) | 2549 (10.31) | 3479 (14.08) | 4373 (17.70) | < 0.0001 |
Dyslipidemia, n (%) | 5757 (5.82) | 751 (3.04) | 1044 (4.22) | 1613 (6.53) | 2349 (9.50) | < 0.0001 |
Antihypertensive drugs, n (%) | 2311 (2.34) | 137 (0.55) | 246 (1.00) | 513 (2.08) | 1415 (5.73) | < 0.0001 |
Antidiabetic drugs, n (%) | 845 (0.85) | 97 (0.39) | 156 (0.63) | 201 (0.81) | 391 (1.58) | < 0.0001 |
Lipid-lowering drugs, n (%) | 10,670 (10.79) | 1647 (6.66) | 2188 (8.85) | 3050 (12.34) | 3785 (15.32) | < 0.0001 |
Fasting plasma glucose, mmol/L | 5.11 (4.66–5.71) | 4.78 (4.37–5.20) | 5.01 (4.62–5.46) | 5.24 (4.80–5.82) | 5.67 (5.02–6.90) | < 0.0001 |
Total cholesterol, mmol/L | 4.92 (4.28–5.59) | 4.59 (4.03–5.20) | 4.89 (4.29–5.46) | 5.07 (4.47–5.71) | 5.19 (4.44–5.94) | < 0.0001 |
Triglycerides, mmol/L | 1.27 (0.89–1.93) | 0.70 (0.58–0.82) | 1.10 (0.98–1.22) | 1.56 (1.36–1.79) | 2.76 (2.18–3.90) | < 0.0001 |
HDL-C, mmol/L | 1.50 (1.28–1.76) | 1.54 (1.30–1.80) | 1.52 (1.31–1.77) | 1.48 (1.27–1.74) | 1.47 (1.25–1.74) | < 0.0001 |
LDL-C, mmol/L | 2.33 (1.82–2.83) | 2.13 (1.60–2.72) | 2.37 (1.91–2.82) | 2.41 (1.97–2.90) | 2.38 (1.82–2.88) | < 0.0001 |
Hs-CRP, mg/dL | 0.80 (0.30–2.20) | 0.60 (0.21–1.90) | 0.73 (0.30–2.00) | 0.90 (0.34–2.20) | 1.04 (0.40–2.66) | < 0.0001 |