Fig. 2
From: Dual SGLT-1 and SGLT-2 inhibition improves left atrial dysfunction in HFpEF
a Representative examples of CaT during 1 Hz electric stimulation and 2 mM extracellular [Ca2+]. Related data of b diastolic Ca2+ and c CaT amplitude. d Averaged CaT (all cells per group) during 3 Hz electric stimulation and 5 mM extracellular [Ca2+]. Related data of e diastolic Ca2+, f CaT amplitude and g time-to-peak. h Representative examples of CaT at 1 Hz electric stimulation after 1 h incubation in glucose-deprived buffer (left) and after reintroduction of 30 mM glucose for 1 min (right). Red, dashed lines indicate diastolic Ca2+ at baseline, arrows indicate stimulation triggers. i Related data of diastolic Ca2+ before (man) and after treatment with glucose (glc); j change of diastolic Ca2+. Statistical analysis: two-way ANOVA followed by post-hoc Bonferroni. p-values: 10.03, 20.02, 30.01, 4< 0.001, 50.001, 60.046. n = cells derived from 6 animals per group