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Table 3 Risk of cancer death according to each individual parameter at baseline

From: History of lower-limb complications and risk of cancer death in people with type 2 diabetes

 

Hazard Ratio

95% CI

p

Female sex

0.62

0.49–0.79

 < 0.0001

Region of origin: established market economies (vs. Asia)

1.87

1.43–2.44

 < 0.0001

Region of origin: Eastern Europe (vs. Asia)

1.68

1.21–2.33

0.002

Region of origin: established market economies (vs. Eastern Europe)

1.11

0.84–1.48

0.46

Age (per 1 SD increase)

1.82

1.63–2.03

 < 0.0001

Duration of diabetes (per 1 SD increase)

1.01

0.91–1.13

0.83

Body mass index (per 1 SD increase)

1.08

0.97–1.20

0.14

Waist circumference (per 1 SD increase)

1.23

1.11–1.37

 < 0.0001

Systolic blood pressure (per 1 SD increase)

1.07

0.96–1.19

0.23

Diastolic blood pressure (per 1 SD increase)

0.91

0.81–1.02

0.10

Mini-Mental State Examination score (< 28 vs. ≥ 28)

1.30

1.01–1.67

0.04

Education accomplishment (≤ 15 vs. ≥ 16 years)

1.44

1.15–1.80

0.001

HbA1c (per 1 SD increase)

1.04

0.93–1.16

0.45

Urinary albumin to creatinine ratio (per 1SD increase)

1.08

0.97–1.21

0.16

Estimated glomerular filtration rate (per 1 SD increase)

0.82

0.73–0.91

0.0003

Serum total cholesterol (per 1 SD increase)

0.85

0.75–0.95

0.007

Serum HDL cholesterol (per 1 SD increase)

0.88

0.78–0.99

0.03

Serum LDL cholesterol (per 1 SD increase)

0.84

0.75–0.95

0.004

Serum triglycerides (per 1 SD increase)

0.97

0.86–1.09

0.60

History of coronary arterial disease

0.91

0.69–1.20

0.52

History of cerebrovascular disease

0.96

0.68–1.34

0.79

History of diabetic kidney disease

1.38

1.08–1.77

0.01

History of diabetic retinopathy

1.34

0.96–1.89

0.09

History of dementia

0.63

0.16–2.52

0.51

History of current smoking

1.21

0.90–1.61

0.20

History of ever smoking

1.67

1.33–2.08

 < 0.0001

History of past alcohol drinking

1.28

1.02–1.60

0.03

History of current alcohol drinking

1.27

1.01–1.60

0.04

Use of Metformin

0.75

0.60–0.93

0.01

Use of insulin therapy

1.17

0.48–2.83

0.72

Use of antihypertensive treatment

0.88

0.70–1.11

0.27

Use of antiplatelet drugs

0.92

0.74–1.15

0.48

Use of statins

0.95

0.75–1.22

0.71

  1. Cox proportional hazards survival regressive analysis for each variable adjusted for study allocations. SD standard deviation
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Cardiovascular Diabetology

ISSN: 1475-2840