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Table 1 Clinical characteristics of the cohort (n = 200)

From: Reduced oxidized LDL in T2D plaques is associated with a greater statin usage but not with future cardiovascular events

 

All

No T2D (n = 129)

T2D (n = 71)

Age (years)

69.3 (SD 8.6)

69 (SD 8.8)

70 (SD 8.3)

Sex–Males (%)

134 (67%)

86 (67%)

48 (68%)

Smoking- current/non smokers (%)

65/40 (33/20)

44/24 (34/19)

21/16 (30/23)

BMIa

27 (SD 3.9)

26 (SD 3.7)

28 (SD 3.9)***

Degree of stenosis (%)

90 (IQR 80-95)

90 (IQR 80-95)

90 (IQR 75-95)

Hypertension (%)

147 (74)

94 (73)

53 (75)

hsCRP (mg/L)b

3.9 (IQR 2.0-6.6)

3.8 (IQR 2-6.7)

4.2 (IQR 1.9-6.6)

HbA1c (mmol/mol)e

44 (IQR 38-56)

39 (IQR 36-41)

56 (IQR 47-66)***

Plasma lipoproteins (mmol/L)

 Total cholesterol

4.4 (SD 1.1)

4.6 (SD 1.1)

4.2 (SD 1.1)*

 LDLc

2.5 (IQR 1.9-3.2)

2.6 (IQR 2.0-3.3)

2.2 (IQR 1.6-3.0)**

 HDLd

1.1 (IQR 0.9-1.3)

1.1 (IQR 0.9-1.3)

1.0 (IQR 0.8-1.3)

 Triglycerides

1.3 (IQR 1.0-1.8)

1.2 (IQR 0.9-1.7)

1.6 (IQR 1.0-2.1)**

Blood glucose lowering treatment, n(%)

 Life style changes

11 (6%)

–

11 (15%)

 Oral glucose lowering treatment

37 (19%)

–

37 (52%)

 Insulin

22 (11%)

–

22 (31%)

 Insulin and oral glucose lowering

12 (6%)

–

12 (17%)

Blood pressure lowering treatment, n(%)

 RAAS inhibitor

101 (51%)

58 (45%)

43 (61%)*

 Beta blocker

98 (49%)

59 (46%)

39 (55%)

Statin treatment, n(%)

164 (82%)

100 (78%)

64 (90%)*

  1. Categorical variables are expressed in total amount and percentages. Continuous variables as median and interquartile range (IQR) or mean and standard deviation (SD)
  2. aBMI Body mass index
  3. bhsCRP high sensitive CRP
  4. cLDL Low-density lipoprotein cholesterol
  5. dHDL High-density lipoprotein
  6. e HbA1c hemoglobin A1c, was available for 62% (n = 124) of the cohort. Hypertension defined as: anti-hypertensive treatment or systolic pressure > 140 mmHg. Level of significance between no diabetes and T2D patients is marked by *p < 0.05, **p < 0.01 and ***p < 0.005