| 1st Quartile (n = 43) | 2nd Quartile (n = 45) | 3rd Quartile (n = 44) | 4th Quartile (n = 44) | P value |
---|---|---|---|---|---|
IVSd (mm) | |||||
 Baseline | 9.84 ± 1.49 | 10.93 ± 2.02¶ | 10.92 ± 1.98 | 11.12 ± 1.97†|  < 0.01 |
 Follow-up | 10.21 ± 1.52 | 11.83 ± 1.95¶ | 11.31 ± 1.89§ | 12.16 ± 1.86†|  < 0.01 |
 Change | 0.37 ± 1.15 | 0.91 ± 1.01 | 0.39 ± 1.28 | 1.04 ± 1.28 |  < 0.05 |
LVPWd (mm) | |||||
 Baseline | 9.29 ± 1.10 | 8.93 ± 1.16 | 9.19 ± 1.26 | 9.69 ± 1.43# |  < 0.05 |
 Follow-up | 9.04 ± 1.30 | 9.69 ± 1.49 | 9.55 ± 1.63 | 10.02 ± 1.50†|  < 0.05 |
 Change | − 0.24 ± 1.32 | 0.76 ± 1.50¶ | 0.36 ± 1.20 | 0.34 ± 1.40 |  < 0.01 |
LV mass (g) | |||||
 Baseline | 137.63 ± 33.74 | 151.00 ± 43.78 | 147.46 ± 38.30 | 168.01 ± 45.08†|  < 0.01 |
 Follow-up | 139.45 ± 31.84 | 160.91 ± 43.53 | 156.20 ± 38.65 | 180.95 ± 45.57†& |  < 0.01 |
 Change | 2.24 ± 10.97 | 9.91 ± 12.10¶ | 8.74 ± 12.23 | 12.94 ± 16.93†|  < 0.01 |
LVEF (%) | Â | Â | Â | Â | Â |
 Baseline | 66.02 ± 3.71 | 65.50 ± 4.16 | 65.40 ± 4.64 | 65.61 ± 4.04 | 0.92 |
 Follow-up | 63.81 ± 3.45 | 64.42 ± 4.46 | 62.98 ± 5.16 | 63.64 ± 5.01 | 0.53 |
 Change | − 2.27 ± 4.31 | − 1.24 ± 4.58 | − 2.38 ± 6.70 | − 1.80 ± 5.14 | 0.75 |
E/A | Â | Â | Â | Â | Â |
 Baseline | 1.05 ± 0.27 | 0.91 ± 0.24 | 0.97 ± 0.41 | 0.90 ± 0.55 | 0.27 |
 Follow-up | 0.93 ± 0.22 | 0.84 ± 0.18 | 0.91 ± 0.39 | 0.78 ± 0.16 |  < 0.05 |
 Change | − 0.12 ± 0.24 | − 0.07 ± 0.19 | − 0.06 ± 0.17 | − 0.04 ± 0.21 | 0.34 |
e′ septal (cm/s) | |||||
 Baseline | 8.57 ± 2.11 | 7.91 ± 2.14 | 7.36 ± 1.59§ | 6.91 ± 1.99†|  < 0.01 |
 Follow-up | 7.41 ± 1.80 | 7.24 ± 1.81 | 7.30 ± 1.96 | 6.07 ± 1.72†#& |  < 0.01 |
 Change | − 1.15 ± 1.65 | − 0.67 ± 2.08 | − 0.07 ± 1.67 | − 0.79 ± 2.03 | 0.06 |
e′ lateral (cm/s) | |||||
 Baseline | 11.30 ± 2.56 | 10.65 ± 2.46 | 10.16 ± 2.41 | 9.17 ± 2.33†# |  < 0.01 |
 Follow-up | 10.21 ± 2.47 | 9.93 ± 2.03 | 9.18 ± 2.09 | 8.23 ± 2.48†# |  < 0.01 |
 Change | − 1.10 ± 1.77 | − 0.74 ± 2.01 | − 0.98 ± 1.80 | − 0.93 ± 1.87 | 0.86 |
Average E/e′ | |||||
 Baseline | 8.45 ± 2.13 | 8.39 ± 3.25 | 9.28 ± 2.18 | 9.80 ± 2.96 |  < 0.05 |
 Follow-up | 9.12 ± 2.87 | 8.70 ± 2.35 | 9.72 ± 2.67 | 11.66 ± 3.63†#& |  < 0.01 |
 Change | 0.68 ± 1.65 | 0.34 ± 2.31 | 0.44 ± 1.93 | 1.93 ± 2.25†#& |  < 0.01 |
LAVi (ml/m2) | |||||
 Baseline | 31.86 ± 9.02 | 29.63 ± 7.04 | 29.94 ± 9.33 | 33.21 ± 10.44 | 0.61 |
 Follow-up | 29.10 ± 8.90 | 28.63 ± 8.74 | 30.71 ± 9.52 | 32.26 ± 8.42 | 0.25 |
 Change | − 2.23 ± 9.03 | − 0.34 ± 7.60 | 0.06 ± 8.68 | − 0.68 ± 6.93 | 0.21 |