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Table 2 Comparison of echocardiography parameters of study participants stratified by serum AFABP quartiles

From: Association between adipocyte fatty acid-binding protein with left ventricular remodelling and diastolic function in type 2 diabetes: a prospective echocardiography study

 

1st Quartile (n = 43)

2nd Quartile (n = 45)

3rd Quartile (n = 44)

4th Quartile (n = 44)

P value

IVSd (mm)

 Baseline

9.84 ± 1.49

10.93 ± 2.02¶

10.92 ± 1.98

11.12 ± 1.97†

 < 0.01

 Follow-up

10.21 ± 1.52

11.83 ± 1.95¶

11.31 ± 1.89§

12.16 ± 1.86†

 < 0.01

 Change

0.37 ± 1.15

0.91 ± 1.01

0.39 ± 1.28

1.04 ± 1.28

 < 0.05

LVPWd (mm)

 Baseline

9.29 ± 1.10

8.93 ± 1.16

9.19 ± 1.26

9.69 ± 1.43#

 < 0.05

 Follow-up

9.04 ± 1.30

9.69 ± 1.49

9.55 ± 1.63

10.02 ± 1.50†

 < 0.05

 Change

− 0.24 ± 1.32

0.76 ± 1.50¶

0.36 ± 1.20

0.34 ± 1.40

 < 0.01

LV mass (g)

 Baseline

137.63 ± 33.74

151.00 ± 43.78

147.46 ± 38.30

168.01 ± 45.08†

 < 0.01

 Follow-up

139.45 ± 31.84

160.91 ± 43.53

156.20 ± 38.65

180.95 ± 45.57†&

 < 0.01

 Change

2.24 ± 10.97

9.91 ± 12.10¶

8.74 ± 12.23

12.94 ± 16.93†

 < 0.01

LVEF (%)

     

 Baseline

66.02 ± 3.71

65.50 ± 4.16

65.40 ± 4.64

65.61 ± 4.04

0.92

 Follow-up

63.81 ± 3.45

64.42 ± 4.46

62.98 ± 5.16

63.64 ± 5.01

0.53

 Change

− 2.27 ± 4.31

− 1.24 ± 4.58

− 2.38 ± 6.70

− 1.80 ± 5.14

0.75

E/A

     

 Baseline

1.05 ± 0.27

0.91 ± 0.24

0.97 ± 0.41

0.90 ± 0.55

0.27

 Follow-up

0.93 ± 0.22

0.84 ± 0.18

0.91 ± 0.39

0.78 ± 0.16

 < 0.05

 Change

− 0.12 ± 0.24

− 0.07 ± 0.19

− 0.06 ± 0.17

− 0.04 ± 0.21

0.34

e′ septal (cm/s)

 Baseline

8.57 ± 2.11

7.91 ± 2.14

7.36 ± 1.59§

6.91 ± 1.99†

 < 0.01

 Follow-up

7.41 ± 1.80

7.24 ± 1.81

7.30 ± 1.96

6.07 ± 1.72†#&

 < 0.01

 Change

− 1.15 ± 1.65

− 0.67 ± 2.08

− 0.07 ± 1.67

− 0.79 ± 2.03

0.06

e′ lateral (cm/s)

 Baseline

11.30 ± 2.56

10.65 ± 2.46

10.16 ± 2.41

9.17 ± 2.33†#

 < 0.01

 Follow-up

10.21 ± 2.47

9.93 ± 2.03

9.18 ± 2.09

8.23 ± 2.48†#

 < 0.01

 Change

− 1.10 ± 1.77

− 0.74 ± 2.01

− 0.98 ± 1.80

− 0.93 ± 1.87

0.86

Average E/e′

 Baseline

8.45 ± 2.13

8.39 ± 3.25

9.28 ± 2.18

9.80 ± 2.96

 < 0.05

 Follow-up

9.12 ± 2.87

8.70 ± 2.35

9.72 ± 2.67

11.66 ± 3.63†#&

 < 0.01

 Change

0.68 ± 1.65

0.34 ± 2.31

0.44 ± 1.93

1.93 ± 2.25†#&

 < 0.01

LAVi (ml/m2)

 Baseline

31.86 ± 9.02

29.63 ± 7.04

29.94 ± 9.33

33.21 ± 10.44

0.61

 Follow-up

29.10 ± 8.90

28.63 ± 8.74

30.71 ± 9.52

32.26 ± 8.42

0.25

 Change

− 2.23 ± 9.03

− 0.34 ± 7.60

0.06 ± 8.68

− 0.68 ± 6.93

0.21

  1. A, trans-mitral late diastolic peak velocity; AFABP, adipocyte fatty acid-binding protein; E, trans-mitral early diastolic peak velocity; e′, early diastolic peak velocity of mitral valve at septal or lateral annulus; IVSd, inter-ventricular septal dimension at end-diastole; LAVi, left atrial volume index; LV, left ventricular; LVEF, LV ejection fraction; LVPWd, LV posterior wall thickness at end-diastole
  2. ¶ P < 0.05 between 1st quartile and 2nd quartile
  3. § P < 0.05 between 1st quartile and 3rd quartile
  4. † P < 0.05 between 1st quartile and 4th quartile
  5. # P < 0.05 between 2nd quartile and 4th quartile
  6. & P < 0.05 between 3rd quartile and 4th quartile