Clinical event |  < 120/ < 70 mmHg | 120–129/70–79 mmHg | 130–139/80–89 mmHg | 140–149/90–99 mmHg |  ≥ 150/ ≥ 100 mmHg |
---|---|---|---|---|---|
Total | Â | Â | Â | Â | Â |
 Events | 1123 | 7625 | 13,764 | 8188 | 4696 |
 Person-years | 92,622 | 567,439 | 983,762 | 484,528 | 204,774 |
 Incidence (events/100,000 person-years) | 1212 | 1344 | 1399 | 1690 | 2293 |
 Adjusted HR (95% CI) | 0.85 (0.80–0.90) | 0.94 (0.92–0.97) | Ref | 1.12 (1.09–1.15) | 1.33 (1.29–1.37) |
 < 50 years | |||||
 Events | 113 | 951 | 1763 | 874 | 430 |
 Person-years | 30,886 | 167,650 | 288,016 | 119,956 | 39,039 |
 Incidence (events/100,000 person-years) | 366 | 567 | 612 | 729 | 1101 |
 Adjusted HR (95% CI) | 0.74 (0.61–0.90) | 0.96 (0.89–1.04) | Ref | 1.20 (1.10–1.30) | 1.79 (1.61–1.99) |
50–59 years | |||||
 Events | 265 | 1860 | 3409 | 1815 | 877 |
 Person-years | 27,949 | 182,438 | 318,830 | 146,385 | 55,314 |
 Incidence (events/100,000 person-years) | 948 | 1020 | 1069 | 1240 | 1585 |
 Adjusted HR (95% CI) | 0.87 (0.77–0.99) | 0.94 (0.89–1.00) | Ref | 1.16 (1.10–1.23) | 1.43 (1.32–1.54) |
60–69 years | |||||
 Events | 425 | 2999 | 5361 | 3301 | 1916 |
 Person-years | 24,115 | 158,546 | 276,831 | 155,068 | 72,302 |
 Incidence (events/100,000 person-years) | 1762 | 1892 | 1937 | 2129 | 2650 |
 Adjusted HR (95% CI) | 0.86 (0.78–0.95) | 0.97 (0.92–1.01) | Ref | 1.09 (1.05–1.14) | 1.32 (1.25–1.39) |
 ≥ 70 years | |||||
 Events | 320 | 1815 | 3231 | 2198 | 1473 |
 Person-years | 9670 | 58,803 | 100,083 | 63,116 | 38,117 |
 Incidence (events/100,000 person-years) | 3309 | 3087 | 3228 | 3482 | 3864 |
 Adjusted HR (95% CI) | 0.99 (0.88–1.11) | 0.95 (0.89–1.00) | Ref | 1.08 (1.03–1.14) | 1.17 (1.10–1.25) |