Table 1 Baseline characteristics by prior additional CVD status

Age (years)

59.0 ± 9.6

62.3 ± 9.3

 < 0.001

Female, n (%)

980 (28%)

799 (34%)

 < 0.001

Race, n (%)

 < 0.001

 Asian

582 (17%)

176 (8%)

 Black or African American

116 (3%)

88 (4%)

 White

2501 (71%)

1907 (82%)

 Other

328 (9%)

154 (7%)

Systolic blood pressure (mmHg)

130 ± 16

132 ± 16

 < 0.001

Diastolic blood pressure (mmHg)

78 ± 9

78 ± 9

0.95

Pulse pressure (mmHg)

52 ± 13

54 ± 13

 < 0.001

Heart rate (bpm)

70 ± 9

70 ± 9

0.89

BMI (kg/m²)

29.7 ± 5.7

30.7 ± 5.6

 < 0.001

Diabetes duration (years)

8.5 ± 7.8

10.4 ± 8.7

 < 0.001

HbA1c (%)

7.7 ± 1.3

7.7 ± 1.3

0.48

eGFR (ml/min/1.73m²)

79 ± 21

71 ± 21

 < 0.001

Albuminuria (mg/g)

 < 0.001

 < 30 (normal)

2697 (77%)

1633 (70%)

 ≥ 30–< 300 (micro)

631 (18%)

494 (21%)

 ≥ 300 (macro)

184 (5%)

191 (8%)

BNP (pg/ml) median [IQR]

90 [44–176]

138 [63–293]

 < 0.001

Smoking status, n (%)

0.005

 Current

421 (12%)

246 (11%)

 Former

1646 (47%)

1019 (44%)

 Never

1460 (41%)

1060 (46%)

MI history other than index ACS, n (%)

0 (0.0%)

1341 (58%)

NA

Stroke history, n (%)

0 (0.0%)

314 (14%)

NA

Heart failure history, n (%)

0 (0.0%)

1317 (57%)

NA

Coronary revascularization history, n (%)

2527 (72%)

1554 (67%)

 < 0.001

STEMI at index event, n (%)

1817 (52%)

756 (33%)

 < 0.001

Left ventricular ejection fraction^a (percent)

53 ± 11

48 ± 13

 < 0.001

Insulin, n (%)

1239 (35%)

1042 (45%)

 < 0.001

Statin, n (%)

3333 (95%)

2099 (90%)

 < 0.001

Beta blocker, n (%)

2904 (82%)

2049 (88%)

 < 0.001

Calcium channel blocker, n (%)

652 (19%)

629 (27%)

 < 0.001

Diuretic, n (%)

1085 (31%)

1223 (53%)

 < 0.001

ACE inhibitor, n (%)

2095 (59%)

1437 (62%)

0.07

ARB, n (%)

910 (26%)

645 (28%)

0.10

Alpha blocker, n (%)

136 (4%)

122 (5%)

0.011

Potassium sparing agents, n (%)

347 (10%)

508 (22%)

 < 0.001