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Table 1 Baseline characteristics

From: Visit-to-visit fasting plasma glucose variability is associated with left ventricular adverse remodeling in diabetic patients with STEMI

Tertiles of CV of FPG

T1 ≤ 0.157

T2 0.157–0.249

T3 > 0.249

P value

n

146

146

145

 

Demographic characteristics & clinical measures

 Male

126 (86.3)

124 (84.9)

120 (82.8)

0.702

 Age, years

61.79 ± 11.24

63.15 ± 11.54

63.96 ± 11.67

0.268

 BMI, kg/m2

24.68 ± 3.12

25.18 ± 4.78

25.28 ± 3.48

0.387

 Systolic BP, mmHg

122.26 ± 17.43

124.47 ± 19.92

120.75 ± 20.56

0.284

 Diastolic BP, mmHg

82.78 ± 81.65

75.56 ± 12.19

72.83 ± 12.42

0.217

Medical history

 Hypertension

76 (52.1)

104 (71.2)

92 (63.4)

0.003

 Duration of diabetes, years

6.38 ± 3.93

6.68 ± 3.90

10.77 ± 7.16

< 0.001

 Current smoker

68 (46.6)

76 (52.1)

65 (44.8)

0.456

Laboratory values

 HbA1C,  %

6.23 ± 0.94

6.69 ± 1.41

7.54 ± 1.70

< 0.001

 FPG, mmol/L

5.77 (5.12–6.70)

7.67 (6.76–9.33)

10.70 (7.91–13.34)

< 0.001

 PPG (2 h), mmol/L

8.65 (6.88–11.27)

11.18 (7.59–12.97)

11.79 (9.71–15.56)

< 0.001

 Fasting insulin, µU/mL

10.72 (8.35–15.52)

9.42 (5.80–15.80)

12.00 (8.33–24.78)

0.003

 Postparandial insulin (2 h), µU/mL

56.23 (33.60–109.03)

37.31 (16.96–65.80)

27.92 (13.27–75.63)

< 0.001

 Triglyceride, mmol/L

1.63 (1.32–2.21)

1.54 (1.02–2.05)

1.58 (1.11–2.02)

0.033

 Total cholesterol, mmol/L

4.36 ± 0.95

4.53 ± 1.18

4.56 ± 1.35

0.273

 HDL cholesterol, mmol/L

0.99 ± 0.28

1.02 ± 0.27

1.01 ± 0.24

0.734

 LDL cholesterol, mmol/L

2.57 ± 0.86

2.81 ± 0.95

2.89 ± 1.15

0.020

 Non-HDL cholesterol,

3.36 ± 0.96

3.51 ± 1.12

3.53 ± 1.32

0.388

eGFR, mL/min/1.73m2

93.90 ± 15.42

97.26 ± 22.73

97.93 ± 33.81

0.343

 hsCRP, mg/L

3.01 (1.28–8.28)

2.73 (0.84–19.00)

4.88 (1.79–26.90)

0.062

 Peak troponin I

4.23 (0.40–15.85)

8.37 (3.34–48.53)

8.80 (4.63–69.11)

< 0.001

Diseased vessels

 1-vessel

50 (34.2)

50 (34.2)

33 (22.8)

 

 2-vessel

52 (35.6)

64 (43.8)

61 (42.1)

0.040

 3-vessel

44 (30.1)

32 (21.9)

51 (35.2)

 

 MVD

96 (65.8)

96 (65.8)

112 (77.2)

0.056

Culprit vessel

 LM

0 (0.0)

2 (1.3)

4 (2.3)

 

 LAD

86 (55.1)

98 (62.0)

86 (50.0)

 

 LCX

28 (17.9)

20 (12.7)

39 (22.7)

0.100

 RCA

42 (26.9)

38 (24.1)

43 (25.0)

 

Medication use, n(%)

 Aspirin

138 (94.5)

138 (94.5)

133 (91.7)

0.546

 P2Y12 inhibitor

138 (94.5)

134 (91.8)

130 (89.7)

0.311

 Beta blocker

134 (91.8)

122 (83.6)

122 (84.1)

0.064

 ACEI/ARB

112 (76.7)

110 (75.3)

105 (72.4)

0.694

 CCB

6 (4.1)

14 (9.6)

25 (17.2)

0.001

 Statin

104 (71.2)

120 (82.2)

132 (91.0)

< 0.001

 Biguanides

14 (9.6)

20 (13.7)

38 (26.2)

< 0.001

 Sulfonylureas

6 (4.1)

16 (11.0)

24 (16.6)

0.002

 Meglitinides

4 (2.7)

0 (0.0)

12 (8.3)

0.002

 Glucosidase inhibitor

80 (54.8)

66 (45.2)

60 (41.4)

0.064

 SGLT2 inhibitor

2 (1.4)

0 (0.0)

1 (0.7)

0.548

 OHA

92 (63.0)

84 (57.5)

86 (59.3)

0.644

 Insulin

4 (2.7)

8 (5.5)

26 (17.9)

< 0.001

  1. ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, BMI body mass index, BP blood pressure, CCB calcium channel blockers, CV coefficient of variation, eGFR estimated glomerular filtration rate, FPG fasting plasma glucose, HbA1c glycated hemoglobin A1c, HDL high-density lipoprotein, hsCRP high-sensitivity C-reactive protein, LAD left anterior descending branch, LCX left circumflex branch, LDL low-density lipoprotein, LM left main coronary artery, MVD multi-vessel disease, OHA oral hypoglycemic agent, PPG postprandial plasma glucose, RCA right coronary artery, SGLT2 sodium-dependent glucose transporters 2