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Table 4 Characteristics of OCT-derived macrophage accumulation in DM and non-DM patients with ACS

From: Macrophage accumulation within coronary arterial wall in diabetic patients with acute coronary syndrome: a study with in-vivo intravascular imaging modalities

 

DM (n = 20)

non DM (n = 20)

p value

Total normalized M-Vol (mm3/mm)

9.5 × 10−3(4.2 × 10−3 − 12.5 × 10−3)

2.9 × 10−3(1.4 × 10−3  − 11.3 × 10−3)

0.015

Normalized M-Vol in high SS region (mm3/mm)

1.9 × 10−3(0.4 × 10−3 − 7.8 × 10−3)

2.1 × 10−3(0.5 × 10−3 − 8.0 × 10−3)

0.999

normalized M-Vol in low SS region (mm3/mm)

4.0 × 10−3(2.2 × 10−3 − 9.7 × 10−3)

0.8 × 10−3(0.2 × 10−3 − 2.1 × 10−3)

0.002

p value between high SS and low SS regions

0.314

0.096

 

Total M-density

9.9 × 10−4(4.1 × 10−4 − 12.9 × 10−4)

4.5 × 10−4(2.1 × 10−4 − 11.9 × 10−4)

0.060

M-density in high SS region

5.6 × 10−4(1.1 × 10−4 − 18.8 × 10−4)

7.1 × 10−4(1.4 × 10−4 − 16.5 × 10−4)

0.779

M-density in low SS region

6.5 × 10−4(4.5 × 10−4 − 15.1 × 10−4)

1.5 × 10−4(0.5 × 10−4 − 4.5 × 10−4)

0.003

p value between high SS and low SS regions

0.565

0.030

 
  1. Values are expressed as median value (confidence interval). M-vol, macrophage accumulation volume; SS, shear stress; M-density, macrophage accumulation density per IVUS-derived plaque volume