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Table 1 Pretreatment demographic and clinical characteristics of study subjects included in final analysis

From: Omega-3 polyunsaturated fatty acid supplementation versus placebo on vascular health, glycaemic control, and metabolic parameters in people with type 1 diabetes: a randomised controlled preliminary trial

 

n-3PUFA

Placebo

P value

Total n

10

10

–

Gender

  

0.582b

 Male

9

7

–

 Female

1

3

–

Insulin therapy (n)

  

0.370b

 Multiple daily injection

7

4

–

Basal insulin

4G; 2D; 1DG

1D; 1DG; 1G; 1I

 

Bolus insulin

5A; 2L

3A; 1GL

 

 Continuous subcutaneous insulin infusion

3A

3A; 3L

–

Total daily insulin dose (IU)

41.3 ± 7.7

40.1 ± 9.5

0.776a

Medication

1 Atorvastatin 1 Lisinopril

1 Atorvastatin, Metformin, and Nefopam

1 Levothyroxine

1 Lisinopril and Pravastatin

1.000b

Age (y)

32 ± 12

36 ± 17

0.524a

Body mass index (kg/m2)

25.13 ± 3.43

28.14 ± 6.38

0.205a

Duration of diabetes (y)

15 ± 13

21 ± 12

0.284a

Age of diagnosis (y)

17 ± 8

16 ± 8

0.590a

Glycosylated haemoglobin (% [mmol/mol])

7.10 ± 3.20 [54.20 ± 11.95]

7.90 ± 3.40 [62.89 ± 13.81]

0.160a

Systolic blood pressure (mm/Hg)

127.3 ± 10.6

132.9 ± 11.7

0.275a

Diastolic blood pressure (mm/Hg)

78.0 ± 10.6

76.8 ± 6.2

0.751a

Triglycerides (mmol/L)

0.94 ± 0.58

1.04 ± 0.62

0.726a

Cholesterol (mmol/L)

4.25 ± 0.88

4.09 ± 0.45

0.637a

Omega-3 index (%)

4.93 ± 0.94

4.31 ± 1.15

0.206a

  1. Data presented as mean ± SD. n-3PUFA compared to placebo. Independent samples t tests were performed on metric variables a; Fisher exact tests performed on categorical variables b. n-3PUFA, omega-3 polyunsaturated fatty acid. Omega-3 index calculated as eicosapentaenoic acid plus docosahexaenoic acid. A, Aspart; D, Detemir; DG, Degludec; G, Glargine; GL, Glulisine; I, Isophane; L, Lispro