Table 4 Relation of the GDF-15 level and all-cause death in univariate and multivariate survival analysis
| Â | Independent predictors of all-cause death | |||||
|---|---|---|---|---|---|---|
Univariate Models | Multivariate Models | |||||
HR | 95% CI | P | HR | 95% CI | P | |
Age | 1.97 | 1.04–1.12 | < 0.001 | 1.07 | 1.01–1.09 | 0.01 |
Sex | 1.23 | 0.98–1.37 | 0.09 | – | – | – |
Smoking | 0.87 | 0.80–1.17 | 0.39 | – | – | – |
BMI | 0.99 | 0.95–1.02 | 0.48 | – | – | – |
Hypertension | 0.98 | 0.74–1.28 | 0.87 | – | – | – |
Hyperlipidemia | 1.54 | 1.38–1.76 | 0.02 | 1.48 | 1.38–1.86 | 0.03 |
DM | 1.11 | 0.87–1.42 | 0.42 | – | – | – |
GDF-15 ≤ 1200 ng/L | 1.11 | 0.87–1.42 | 0.42 | – | – | – |
GDF-15 ≤ 1800 ng/L | 1.33 | 0.94–1.56 | 0.13 | – | – | – |
GDF-15 > 1800 ng/L | 2.54 | 1.99–3.09 | < 0.001 | 2.04 | 1.57–2.61 | < 0.001 |