Impacts of triglyceride-glucose index on prognosis of patients with type 2 diabetes mellitus and non-ST-segment elevation acute coronary syndrome: results from an observational cohort study in China

Table 5 Predictive value of TyG index for primary endpoint in different Cox proportional hazards models

	TyG index as a nominal variable^a			TyG index as a continuous variable^b
	HR	95% CI	P value	HR	95% CI	P value
Crude model	4.610	3.253–6.533	< 0.001	3.367	2.677–4.235	< 0.001
Model 1	4.858	3.367–7.011	< 0.001	3.459	2.731–4.381	< 0.001
Model 2	3.774	2.553–5.580	< 0.001	2.900	2.194–3.832	< 0.001
Model 3	3.994	2.699–5.991	< 0.001	3.031	2.294–4.005	< 0.001
Model 4	4.062	2.732–6.040	< 0.001	3.208	2.400–4.289	< 0.001

Model 1: adjusted for age, sex (female), BMI, SBP, DBP, smoking, drinking, duration of diabetes, dyslipidemia, prior MI, PCI, stroke and PVD
Model 2: adjusted for variables included in Model 1 and diagnosis (NSTEMI), TC, HDL-C, eGFR, HbA1c, LVEF
Model 3: adjusted for variables included in Model 2 and SYNTAX score, LM treatment, DCB use, complete revascularization and number of stents
Model 4: adjusted for variables included in Model 3 and DAPT at discharge, DAPT interruption in 12 months, statins at discharge, statins interruption in 12 months, oral hypoglycemic agents (metformin, alpha-glucosidase inhibitor, sulfonylurea, dipeptidyl peptidase 4 inhibitor) at discharge and insulin at discharge
Italic values indicate statistically significant associations
TyG triglyceride glucose, HR hazard ratio, CI confidence interval
^aThe HR was examined regarding lower TyG index as reference (stratified by the optimal cutoff point of TyG index determined by ROC curve analysis)
^bThe HR was examined by per 1-unit increase of TyG index

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