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Table 5 Predictive value of TyG index for primary endpoint in different Cox proportional hazards models

From: Impacts of triglyceride-glucose index on prognosis of patients with type 2 diabetes mellitus and non-ST-segment elevation acute coronary syndrome: results from an observational cohort study in China

  TyG index as a nominal variablea TyG index as a continuous variableb
HR 95% CI P value HR 95% CI P value
Crude model 4.610 3.253–6.533 < 0.001 3.367 2.677–4.235 < 0.001
Model 1 4.858 3.367–7.011 < 0.001 3.459 2.731–4.381 < 0.001
Model 2 3.774 2.553–5.580 < 0.001 2.900 2.194–3.832 < 0.001
Model 3 3.994 2.699–5.991 < 0.001 3.031 2.294–4.005 < 0.001
Model 4 4.062 2.732–6.040 < 0.001 3.208 2.400–4.289 < 0.001
  1. Model 1: adjusted for age, sex (female), BMI, SBP, DBP, smoking, drinking, duration of diabetes, dyslipidemia, prior MI, PCI, stroke and PVD
  2. Model 2: adjusted for variables included in Model 1 and diagnosis (NSTEMI), TC, HDL-C, eGFR, HbA1c, LVEF
  3. Model 3: adjusted for variables included in Model 2 and SYNTAX score, LM treatment, DCB use, complete revascularization and number of stents
  4. Model 4: adjusted for variables included in Model 3 and DAPT at discharge, DAPT interruption in 12 months, statins at discharge, statins interruption in 12 months, oral hypoglycemic agents (metformin, alpha-glucosidase inhibitor, sulfonylurea, dipeptidyl peptidase 4 inhibitor) at discharge and insulin at discharge
  5. Italic values indicate statistically significant associations
  6. TyG triglyceride glucose, HR hazard ratio, CI confidence interval
  7. aThe HR was examined regarding lower TyG index as reference (stratified by the optimal cutoff point of TyG index determined by ROC curve analysis)
  8. bThe HR was examined by per 1-unit increase of TyG index