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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Accumulation of advanced glycation end products (AGEs) is associated with the severity of aortic stenosis in patients with concomitant type 2 diabetes

Fig. 1

Expression of AGEs and RAGE within aortic stenotic valves. Representative microphotographs of aortic stenotic valves dissected from patients with aortic stenosis (nonDM) or aortic stenosis with concomitant type 2 diabetes mellitus (DM). a, b The thickness of the leaflets stained with hematoxylin, c, d the valvular expression of advanced glycation end products (AGEs) and e, f their receptor (RAGE), g, h the expression of reactive oxygen species (ROS) modulator 1 (indirect staining for ROS), and i co-localization of AGEs (green) and RAGE (red). Cell nuclei are stained in blue (DAPI). *Aortic site of the leaflet. Original magnification ×40

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Cardiovascular Diabetology

ISSN: 1475-2840