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Table 2 Prevalence of eligible patients according to the enrollment criteria of CANVAS, DECLARE-TIMI 58, EMPA-REG OUTCOME, and VERTIS-CV

From: Generalizability of sodium-glucose co-transporter-2 inhibitors cardiovascular outcome trials to the type 2 diabetes population: a systematic review and meta-analysis

SGLT2i CVOT

Number of patients (number of studies)

Prevalence (95% CI)

I2 (%)

CANVAS

1,510,378 (5)

36.4 (33.3 to 39.4)

100

DECLARE-TIMI 58

1,619,008 (5)

49.5 (39.7 to 59.3)

100

EMPA-REG OUTCOME

1,703,519 (5)

17.0 (10.6 to 23.4)

100

VERTIS-CV

1,330,334 (4)

19.0 (14.4 to 23.7)

100

  1. SGLT2i CVOT, sodium-glucose co-transporter-2 inhibitor cardiovascular outcome trial