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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Acute dapagliflozin administration exerts cardioprotective effects in rats with cardiac ischemia/reperfusion injury

Fig. 3

The effects of dapagliflozin on cardiac arrhythmia and gap junction-related proteins in rats with I/R injury. a Time to 1st VT/VF, n = 6 per group; b Arrhythmia score, n = 6 per group; c p-Cx43 Ser368/Cx43 protein expression in the ischemic area normalized with that in the remote area, n = 6 per group; and d Representative Western blot bands of p-Cx43 Ser368 and Cx43 proteins expression in the ischemic area and the remote area. *p < 0.05 vs control and p < 0.05 vs pretreatment group. Cx43 connexin, I ischemic area, p-Cx43 Ser638 phosphorylation of Cx43 at serine638, R remote area, VF ventricular fibrillation, VT ventricular tachycardia

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