Table 1 Baseline characteristics of three groups
Variable | Tertile 1 (n = 844) | Tertile 2 (n = 843) | Tertile 3 (n = 844) | P value |
|---|---|---|---|---|
TyG index | 8.467 ± 0.293 | 9.114 ± 0.152 | 9.841 ± 0.403 | < 0.001 |
Age, years | 67.2 ± 6.9 | 66.2 ± 6.7 | 65.6 ± 6.8 | < 0.001 |
Male | 519 (61.5) | 446 (52.9) | 450 (53.3) | < 0.001 |
Duration of diabetes, years | 10.2 ± 8.0 | 9.3 ± 7.3 | 10.0 ± 7.7 | 0.030 |
Newly diagnosed diabetes | 47 (5.6) | 53 (6.3) | 57 (6.8) | 0.596 |
Smoker | 338 (40.0) | 323 (38.3) | 338 (40.4) | 0.703 |
Hypertension | 627 (74.3) | 656 (77.8) | 661 (78.3) | 0.102 |
Family history | 101 (12.0) | 93 (11.0) | 77 (9.1) | 0.157 |
Previous MI | 119 (14.1) | 95 (11.3) | 94 (11.1) | 0.110 |
Previous PCI | 193 (22.9) | 156 (18.5) | 149 (17.7) | 0.015 |
Previous CABG | 44 (5.2) | 29 (3.4) | 29 (3.4) | 0.101 |
Previous stroke | 138 (16.4) | 187 (22.2) | 190 (22.5) | 0.002 |
BMI, kg/m2 | 25.4 ± 2.7 | 25.9 ± 2.7 | 26.4 ± 3.3 | < 0.001 |
SBP, mmHg | 134.9 ± 11.8 | 135.8 ± 12.0 | 136.9 ± 11.4 | 0.003 |
DBP, mmHg | 74.0 ± 10.4 | 74.8 ± 10.6 | 75.9 ± 10.1 | 0.001 |
HR, bpm | 72.9 ± 12.2 | 73.6 ± 12.1 | 74.9 ± 11.5 | 0.003 |
LVEF | 58 ± 8 | 58 ± 8 | 57 ± 9 | 0.294 |
GRACE score | 135 (129–140) | 135 (130–141) | 136 (131–142) | < 0.001 |
Clinical presentation | Â | Â | Â | 0.236 |
 UAP | 692 (82.0) | 672 (79.7) | 654 (77.5) |  |
 NSTEMI | 73 (8.6) | 86 (10.2) | 91 (10.8) |  |
 STEMI | 79 (9.4) | 85 (10.1) | 99 (11.7) |  |
Left main disease | 82 (9.7) | 94 (11.2) | 87 (10.3) | 0.624 |
Multi-vessel disease | 658 (78.0) | 689 (81.7) | 697 (82.5) | 0.037 |
Treatment strategy | Â | Â | Â | 0.001 |
 Medicine therapy | 310 (36.7) | 249 (29.5) | 241 (28.6) |  |
 PCI | 436 (51.7) | 497 (59.0) | 514 (60.9) |  |
 CABG | 98 (11.6) | 97 (11.5) | 89 (10.5) |  |
Laboratory findings | Â | Â | Â | Â |
 Hemoglobin, g/dl | 132.1 ± 15.8 | 133.0 ± 15.4 | 132.5 ± 15.3 | 0.490 |
 FBG, mmol/L, | 7.7 ± 2.8 | 7.9 ± 2.8 | 8.4 ± 3.4 | <0.001 |
 HbA1c,  % | 7.5 ± 1.4 | 7.6 ± 1.4 | 7.8 ± 1.4 | <0.001 |
 TC, mmol/L | 4.40 ± 1.21 | 4.46 ± 1.06 | 4.39 ± 1.10 | 0.367 |
 TG, mmol/L | 1.50 (1.11–2.04) | 1.53 (1.12–2.07) | 1.54 (1.11–2.15) | 0.699 |
 LDL-C, mmol/L | 2.88 ± 1.05 | 2.92 ± 0.93 | 2.90 ± 0.95 | 0.759 |
 HDL-C, mmol/L | 1.10 ± 0.32 | 1.08 ± 0.29 | 1.02 ± 0.28 | < 0.001 |
 Uric acid, umol/L | 305.4 ± 78.4 | 306.4 ± 88.2 | 325.5 ± 106.1 | < 0.001 |
 hs-CRP, mg/L | 1.89 (0.83–4.61) | 1.64 (0.71–4.78) | 1.85 (0.79–4.63) | 0.325 |
 NT-proBNP, pg/ml | 108.1 (49.7–278.6) | 117.8 (85.6–170.7) | 160.8 (95.8–363.2) | < 0.001 |
 eGFR, mL/min | 97.8 ± 20.8 | 96.2 ± 23.7 | 85.5 ± 24.6 | < 0.001 |
Medications at discharge | ||||
Aspirin | 817 (96.8) | 811 (96.2) | 814 (96.4) | 0.799 |
 Clopidogrel/Ticagrelor | 666 (78.9) | 689 (81.7) | 707 (83.8) | 0.036 |
 β-blocker | 513 (60.8) | 545 (64.7) | 586 (69.4) | 0.001 |
 ACEI/ARB | 455 (53.9) | 490 (58.1) | 500 (59.2) | 0.066 |
 Statin | 802 (95.0) | 807 (95.7) | 797 (94.4) | 0.468 |
 CCB | 241 (28.6) | 253 (30.0) | 231 (27.4) | 0.485 |
 Nitrate | 478 (56.6) | 459 (54.4) | 453 (53.7) | 0.447 |
 Insulin | 321 (38.0) | 327 (38.8) | 377 (44.7) | 0.010 |