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Table 2 Hazard ratios and 95% confidence intervals for the incidence of hospitalization for heart failure according to the eight groups of transition in obesity sub-phenotypes

From: Hospitalization for heart failure incidence according to the transition in metabolic health and obesity status: a nationwide population-based study

1st examination (2009-2010)2nd examination (2013-2014)nEvents (n)Follow-up duration (person-years)Incidence rate (per 1000 person-years)Hazard ratios (95% confidence intervals)
Model 1Model 2Model 3
MHNOMHNO4,284,989151115,849,397.290.095331 (ref.)1 (ref.)1 (ref.)
MHO420,8791201,535,416.610.078150.831 (0.690, 1.001)1.116 (0.926, 1.345)1.096 (0.909, 1.321)
MUNO546,4225812,049,295.010.283512.916 (2.649, 3.209)1.803 (1.637, 1.986)1.481 (1.341, 1.635)
MUO167,760105615,952.830.170471.792 (1.470, 2.184)1.548 (1.269, 1.887)1.283 (1.051, 1.566)
MHOMHNO252,85899936,371.350.105731.108 (0.904, 1.357)0.610 (0.491, 0.758)0.665 (0.537,0.824)
MHO891,4703183,280,816.520.096931.022 (0.905, 1.153)1.173 (1.039, 1.325)1.132 (1.002, 1.280)
MUNO51,14863192,110.250.327943.366 (2.616, 4.331)2.033 (1.579, 2.616)1.674 (1.299, 2.156)
MUO533,2373541,964,558.090.180191.891 (1.684, 2.123)1.677 (1.493, 1.884)1.385 (1.230, 1.560)
  1. Model 1: unadjusted
  2. Model 2: adjusted for age, sex, smoking history, alcohol consumption, regular exercise, and eGFR
  3. Model 3: adjusted for model 2 + systolic BP, LDL-C, and household income
  4. MHNO metabolically healthy non-obesity, MHO metabolically healthy obesity, MUNO metabolically unhealthy non-obesity, MUO metabolically unhealthy obesity, BP blood pressure, LDL-C low-density lipoprotein cholesterol