Effect of 1,5-anhydroglucitol levels on culprit plaque rupture in diabetic patients with acute coronary syndrome

Table 3 Independent predictors for ruptured culprit plaque

Model 1	Univariate		Multivariate		Model 2	Univariate		Multivariate
Model 1	OR (95% CI)	P value	OR (95% CI)	P value	Model 2	OR (95% CI)	P value	OR (95% CI)	P value
Age	0.992 (0.958, 1.028)	0.672			Age (≥ 65 years)	0.869 (0.414, 1.824)	0.710
Female	1.305 (0.608, 2.801)	0.494			Female	1.305 (0.608, 2.801)	0.494
Current smoking	2.278 (0.961, 5.398)	0.062	2.647 (1.018, 6.883)	0.046	Current smoking	2.278 (0.961, 5.398)	0.062	3.529 (1.292, 9.638)	0.014
Duration of diabetes	1.059 (0.991, 1.130)	0.090			Duration of diabetes (Upper tertile, ≥ 4.8 years)	1.773 (0.851, 3.695)	0.126
Body mass index	1.102 (0.978, 1.243)	0.111			Body mass index (> 30 kg/m²)	1.956 (0.943, 4.055)	0.071
LVEF	0.968 (0.932, 1.006)	0.095			LVEF (< 40%)	1.718 (0.659, 4.479)	0.268
TG	1.353 (0.961, 1.906)	0.084			TG (> 1.70 mmol/L)	1.681 (0.810, 3.490)	0.164
Non-HDL-C	1.904 (1.233, 2.940)	0.004	1.983 (1.236, 3.183)	0.005	non-HDL-C (≥ 4.1 mmol/L)	4.016 (1.736, 9.293)	0.001	4.857 (1.871, 12.61)	0.001
hs-CRP	1.007 (0.940, 1.080)	0.837			hs-CRP (> 3 mg/L)	1.372 (0.668, 2.817)	0.389
1,5-AG	0.914 (0.856, 0.976)	0.007	0.916 (0.852, 0.985)	0.018	1, 5-AG (Lower tertile, < 9.78 µg/mL)	3.631 (1.752, 7.524)	0.001	3.421 (1.446, 8.092)	0.005
FBG	1.176 (1.019, 1.357)	0.026			FBG (≥ 7.0 mmol/L)	1.367 (0.685, 2.729)	0.375
HbA_1c	1.989 (1.083, 3.653)	0.027			HbA_1c (> 7%)	1.996 (0.984, 4.048)	0.055	2.458 (1.081, 5.586)	0.032
Urinary 8-iso-PGF_2α	1.005 (1.000, 1.010)	0.042			Urinary 8-iso-PGF_2α (Upper tertile, > 140 pmol/mmolCr)	2.493 (1.222, 5.085)	0.012

Model 1: Age, duration of diabetes, body mass index, LVEF, TG, non-HDL-C, hs-CRP, 1,5-AG, FBG, HbA_1c and urinary 8-iso-PGF_2α were included as continuous variables. Model 2: All variables were included as categorized variables
LVEF left ventricular ejection fraction, TG triglycerides, non-HDL-C non-high-density lipoprotein cholesterol, hs-CRP high-sensitivity C-reactive protein, 1,5-AG 1,5-anhydroglucitol, FBG fasting blood glucose, HbA_1c hemoglobin A_1c, 8-iso-PGF_2α 8-iso-prostaglandin F_2α

ISSN: 1475-2840