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Table 1 Joinpoint analysis of trends in age-standardized event rates of diabetes-related complications in men with diabetes

From: Trends in diabetes-related complications in Hong Kong, 2001–2016: a retrospective cohort study

Complications

Event rates (per 10,000)

Time period 1

Time period 2

Time period 3

2001

2016

AAPC (95% CI)

Year

APC (95% CI)

Year

APC (95% CI)

Year

APC (95% CI)

CHD

 All ages

477.3

146.0

− 7.6 (− 10.2, − 5.0)*

2001–2003

− 23.1 (− 38.8, − 3.3)*

2003–2016

− 5.0 (− 6.0, − 4.0)*

  

 20–44 years

155.9

55.1

− 7.3 (− 15.0, 1.1)

2001–2003

− 32.2 (− 66.1, 35.7)

2003–2016

− 2.7 (− 6.0, 0.68)

  

 45–64 years

651.9

199.8

− 7.6 (− 9.5, − 5.7)*

2001–2003

− 22.6 (− 32.2, − 11.7)*

2003–2007

− 7.5 (− 12.9, − 1.9)*

2007–2016

− 3.9 (− 4.9, − 3.0)*

 65–74 years

914.3

217.1

− 9.0 (− 11.1, − 6.8)*

2001–2006

− 13.7 (− 15.8, − 11.5)*

2006–2010

− 3.1 (− 8.4, 2.6)

2010–2016

− 8.9 (− 10.5, − 7.3)*

 ≥ 75 years

813.3

281.1

− 6.5 (− 8.7, − 4.2)*

2001–2006

− 9.3 (− 13.7, − 4.6)*

2006–2010

3.6 (− 4.5, 12.4)

2010–2016

− 10.4 (− 12.5, − 8.3)*

Stroke

 All ages

339.5

100.9

− 8.7 (− 9.8, − 7.5)*

2001–2005

− 15.3 (− 19.0, − 11.3)*

2005–2016

− 6.2 (− 7.1, − 5.2)*

  

 20–44 years

56.2

50.3

− 1.8 (–4.6, 1.1)

2001–2016

− 1.8 (− 4.6, 1.1)

    

 45–64 years

338.2

99.7

− 8.3 (− 9.6, − 7.1)*

2001–2005

− 16.3 (− 20.4, − 12.0)*

2005–2016

− 5.3 (− 6.1, − 4.4)*

  

 65–74 years

788.5

157.5

− 10.5 (− 11.5, − 9.5)*

2001–2005

− 15.4 (− 18.8, − 12.0)*

2005–2016

− 8.7 (− 9.5, − 7.9)*

  

 ≥ 75 years

1224.8

289.0

− 9.6 (− 10.6, − 8.6)*

2001–2005

− 14.8 (− 18.3, − 11.1)*

2005–2016

− 7.6 (− 8.3, − 7.0)*

  

Heart failure

 All ages

228.6

83.1

− 6.4 (− 8.0, − 4.7)*

2001–2005

− 12.8 (− 18.3, − 7.0)*

2005–2016

− 3.9 (− 5.2, − 2.7)*

  

 20–44 years

41.6

30.8

1.2 (− 2.4, 4.8)

2001–2016

1.2 (− 2.4, 4.8)

    

 45–64 years

147.5

56.6

− 5.8 (− 8.1, − 3.5)*

2001–2006

− 13.7 (− 19.7, − 7.3)*

2006–2016

− 1.6 (− 3.7, 0.52)

  

 65–74 years

431.9

116.4

− 8.5 (− 10.0, − 7.1)*

2001–2009

− 11.3 (− 13.3, − 9.2)*

2009–2016

− 5.3 (− 7.9, − 2.7)*

  

 ≥ 75 years

1259.2

413.4

− 6.9 (− 8.7, − 5.1)*

2001–2005

− 13.0 (− 19.3, − 6.2)*

    

Hyperglycaemic crisis

 All ages

81.5

33.3

− 6.6 (− 12.4, − 0.44)*

2001–2003

− 30.0 (− 57.9, 16.6)

2003–2016

− 2.4 (− 4.9, 0.24)

  

 20–44 years

151.7

66.0

− 3.9 (− 6.2, − 1.5)*

2001–2016

− 3.9 (− 6.2, − 1.5)*

    

 45–64 years

25.4

10.1

− 7.0 (− 10.6, − 3.2)*

2001–2005

− 22.3 (− 33.0, − 9.9)*

2005–2016

− 0.7 (− 3.5, 2.2)

  

 65–74 years

23.2

4.0

− 12.2 (− 16.3, − 7.9)*

2001–2003

− 42.7 (− 60.4, − 17.2)*

2003–2016

− 6.2 (− 8.4, − 4.0)*

  

 ≥ 75 years

42.3

5.5

− 13.2 (− 17.8, − 8.5)*

2001–2004

− 31.4 (− 48.0, − 9.5)*

2004–2016

− 8.0 (− 10.7, − 5.3)*

  

LEA

 All ages

36.0

11.7

− 5.8 (− 7.2, − 4.4)*

2001–2016

− 5.8 (− 7.2, − 4.4)*

    

 20–44 years

14.1

3.8

− 7.4 (− 19.5, 6.5)

2001–2006

− 8.7 (− 22.4, 7.5)

2006–2010

14.5 (− 17.5, 59.0)

2010–2016

− 18.9 (− 27.5, − 9.3)*

 45–64 years

37.5

18.4

− 2.8 (− 4.7, − 0.91)*

2001–2016

− 2.8 (− 4.7, − 0.91)*

    

 65–74 years

48.0

16.4

− 8.0 (− 9.5, − 6.5)*

2001–2016

− 8.0 (− 9.5, − 6.5)*

    

 ≥ 75 years

123.0

16.6

− 10.5 (− 12.1, − 8.9)*

2001–2016

− 10.5 (− 12.1, − 8.9)*

    
  1. CHD coronary heart disease, LEA lower-extremity amputation, AAPC average annual percent change, APC annual percent change
  2. P < 0.05