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Table 3 Multivariable analyses between possible predictors and silent brain infarct/white matter hyperintensity volume using HOMA-IR instead of TyG index

From: High triglyceride-glucose index is associated with subclinical cerebral small vessel disease in a healthy population: a cross-sectional study

 Silent brain infarctWhite matter hyperintensity
 Adjusted OR (95% CI)P-valueβ (95% CI)P-value
Age1.09 [1.07–1.11]< 0.0010.054 (0.049 to 0.059)< 0.001
Sex, male0.87 [0.63–1.22]0.4260.023 (− 0.063 to 0.109)0.601
Body mass index0.99 [0.94–1.05]0.816− 0.012 (− 0.027 to 0.003)0.124
Use of antihypertensives1.55 [1.07–2.25]0.0210.275 (0.165 to 0.384)< 0.001
Use of antiplatelet agents0.93 [0.51–1.68]0.801− 0.060 (− 0.227 to 0.108)0.484
hs-CRP*1.03 [0.93–1.15]0.553
WBC counts0.029 (0.003 to 0.055)0.031
HOMA-IR*1.32 [1.02–1.71]0.0360.075 (0.013 to 0.137)0.018
  1. HOMA-IR: Homeostatic Model Assessment for Insulin Resistance; hs-CRP: high-sensitivity C-reactive protein; WBC: white blood cell
  2. *These variables were transformed into a log scale
  3. This analysis used a multivariable logistic regression analysis adjusted with P < 0.05 in univariate analysis (age, use of antihypertensives, use of antiplatelet agents, hs-CRP, and HOMA-IR) and sex and BMI
  4. This analysis used a multivariable linear regression analysis adjusted with P < 0.05 in univariate analysis (age, use of antihypertensives, use of antiplatelet agents, White blood cell counts, and HOMA-IR) and sex and BMI