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Table 1 Baseline characteristics of study participants: Tehran Lipid and Glucose Study

From: Change in glucose intolerance status and risk of incident cardiovascular disease: Tehran Lipid and Glucose Study

 

NFG/NGT

(n = 3027)

IFG/IGT

(n = 1067)

Total population

(n = 4094)

P value

Continuous variables

    

 Age (years)

44.2 (11.1)

49.3 (11.6)

45.5 (11.5)

< 0.001

 SBP (mmHg)

116.6 (16.9)

126.0 (19.3)

119.1 (18.1)

< 0.001

 SBP change (mmHg)

− 1.19 (13.1)

− 2.07 (15.5)

− 1.42 (13.83)

0.07

 DBP (mmHg)

76.8 (10.3)

81.2 (10.8)

77.9 (10.6)

< 0.001

 DBP change (mmHg)

− 1.9 (9.09)

− 3.2 (9.5)

− 2.3 (9.20)

< 0.001

 BMI (kg/m2)

27.0 (4.3)

28.6 (4.4)

27.4 (4.3)

< 0.001

 BMI change (kg/m2)

0.8 (1.9)

0.5 (1.9)

0.74 (1.90)

< 0.001

 WC (mmol/L)

88.5 (10.7)

93.8 (10.8)

89.9 (11.0)

< 0.001

 WC change (mmol/L)

3.9 (6.6)

3.16 (6.18)

3.70 (6.54)

0.002

 TC (mmol/L)

5.4 (1.1)

5.7 (1.2)

5.5 (1.1)

< 0.001

 TC change (mmol/L)

− 0.30 (0.76)

− 0.45 (0.84)

− 0.34 (0.78)

< 0.001

 HDL-C (mmol/L)

1.08 (0.28)

1.08 (0.29)

1.08 (0.28)

0.78

 HDL-C change (mmol/L)

− 0.07 (0.23)

− 0.08 (0.25)

− 0.07 (0.24)

0.20

 FPG (mmol/L)

4.8 (0.4)

5.6 (0.5)

5.03 (0.5)

< 0.001

 FPG change (mmol/L)

0.1 (0.5)

− 0.001 (0.8)

0.08 (0.61)

< 0.001

 2 h-PCPG (mmol/L)

5.5 (1.1)

7.6 (1.7)

6.07 (1.6)

< 0.001

 2 h-PCPG change (mmol/L)

0.3 (1.6)

0.02 (2.6)

0.22 (1.92)

< 0.001

 eGFR (mL/min/1.73 m2)

70.6 (11.0)

67.5 (10.8)

69.8 (11.0)

< 0.001

 eGFR change (mL/min/1.73 m2)

2.9 (10.6)

4.4 (11.0)

3.35 (10.72)

< 0.001

Categorical variables

    

 Gender (males)

1334 (44.1%)

463 (43.4%)

1797 (43.9%)

0.72

 Current smoker

421 (13.9%)

107 (10.0%)

528 (12.9%)

0.001

 Hypertension

493 (16.3%)

337 (33.5%)

850 (20.8%)

< 0.001

 Hypercholesterolemia

1659 (54.8%)

723 (67.8%)

2382 (58.2%)

< 0.001

 Antihypertensive drug

130 (4.3%)

107 (10.0%)

237 (5.8%)

< 0.001

 Lipid-lowering drug

58 (1.9%)

47 (4.4%)

105 (2.6%)

< 0.001

 Low physical activitya

2040 (67.4%)

761 (71.3%)

2801 (68.4%)

0.01

 Education

   

< 0.001

  < 6 years

408 (13.5%)

107 (10.0%)

515 (12.6%)

 

  6–12 years

1600 (52.9%)

438 (41.0%)

2038 (49.8%)

 

  > 12 years

1019 (33.7%)

522 (48.9%)

1541 (37.6%)

 

 Marital status

   

0.002

  Single

134 (4.4%)

21 (2%)

155 (3.8%)

 

  Married

2733 (90.3%)

979 (91.8%)

3712 (90.7%)

 

  Divorced/widowed

160 (5.3%)

67 (6.3%)

227 (5.5%)

 
  1. Values are expressed as mean (SD) for continuous variables and n (%) for categorical variables
  2. NFG, normal fasting glucose; NGT, normal glucose tolerance; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; WC, waist circumference; TC, total cholesterol; HDL-C, high density lipoprotein-cholesterol; FPG, fasting plasma glucose; 2 h-PCPG, 2-h post challenge plasma glucose; eGFR, estimated glomerular filtration rate. NFG/NGT defined as those with both NFG and NGT states. IFG/IGT was defined as those with IFG and/or IGT
  3. aLow physical activity was described as subjects participating in physical activity < 3 day/week for participants recruited in first phase or < 600 metabolic equivalent task–minutes (MET)/week for those who entered in the second phase
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Cardiovascular Diabetology

ISSN: 1475-2840