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Fig. 5 | Cardiovascular Diabetology

Fig. 5

From: Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet

Fig. 5

The effects of LIRA treatment on nitrosative, oxidative stress marker and anti-oxidant levels. a Protein expression levels of NT in left ventricle detected by Western blotting. β-actin was used as an internal control. Bands are representative of two separate experiments. b Relative density values of NT. c, d mRNA expressions of NOX-1 and Gpx-1 in Zucker rat myocardium. GAPDH gene was used as an internal control. The ΔΔcT values are shown as the mean ± SEM. Effects of LIRA on Reduced GSH (e), oxidized GSSG (f), and GSH/GSSG ratio (g). N = 5–6 rats per group. The significance of group differences was determined by ANOVA for factors of genotype (G), drug treatment (T) and their interaction term (I)

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Cardiovascular Diabetology

ISSN: 1475-2840