Fig. 2
LIRA treatment improved the capacity to increase perfused segments by NO-mediated dilation in Zucker fa/fa and +/+ rats after 8 weeks on a high-salt diet. a–d Percentage change in 1st to 4th order vessel caliber and visible vessel number during infusions of ACh and ACh stimulation during blockade of prostaglandin production and uncoupling of gap junctions from baseline. Mean ± SEM. The significance of group differences was determined by ANOVA for factors of genotype (G), drug treatment (T) and their interaction (I)