Positive effect of dapagliflozin on left ventricular longitudinal function for type 2 diabetic mellitus patients with chronic heart failure

Table 3 Multiple regression analysis for the association of E/e′ after administration of dapagliflozin

Independent variables	Coefficient	Standard error	T value	p value
Body mass index	− 0.06	1.917	− 0.035	0.973
Systolic blood pressure	− 0.710	0.604	− 1.174	0.254
Heart rate	0.321	0.846	0.380	0.708
HbA1c	− 7.748	16.254	− 0.477	0.639
LVEF	0.204	1.107	0.184	0.856
LV end-systolic volume	− 0.132	0.433	− 0.306	0.763
E/e′	− 1.689	0.863	− 1.958	0.06
GLS	2.572	4.720	0.545	0.591
ΔBody mass index	4.097	3.098	1.322	0.201
ΔSystolic blood pressure	0.250	0.393	− 1.328	0.199
ΔHbA1c	− 2.396	1.805	− 1.328	0.199
ΔGLS	− 1.562	0.720	− 2.169	0.041
ΔLVMI	0.334	0.530	0.630	0.536

ΔHbA1c a relative change in HbA1c 6 months after administration of dapagliflozin, ΔGLS a relative change in GLS 6 months after administration of dapagliflozin, ΔLVMI a relative change in LVMI 6 months after administration of dapagliflozin. Other abbreviations as in Table 1

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