Table 1 Baseline demographic and angiographic characteristics
Variable | Pitavastatin 1 mg (n = 337) | Pitavastatin 4 mg (n = 330) | p-value |
|---|---|---|---|
Age (years) | 64.1 ± 11.9 | 62.2 ± 11.8 | 0.04 |
Male sex | 230 (68.2) | 253 (76.7) | 0.02 |
Body mass index (kg/m2) | 24.3 ± 3.0 | 24.8 ± 3.1 | 0.03 |
Diagnosis | 0.99 | ||
Unstable angina | 210 (72.7) | 209 (72.3) | |
Non-ST elevation MI | 45 (15.6) | 45 (15.6) | |
ST elevation MI | 34 (11.8) | 35 (12.1) | |
Risk factors | |||
Hypertension | 194 (57.6%) | 183 (55.5%) | 0.59 |
Smoking status | 0.01 | ||
Current smoker | 66 (19.6%) | 98 (29.7%) | |
Ex-smoker | 64 (19.0%) | 61 (18.5%) | |
Never smoker | 207 (61.4%) | 171 (51.8%) | |
Alcoholics | 54 (16.0%) | 63 (19.1%) | 0.31 |
Prior MI | 19 (5.4%) | 13 (3.8%) | 0.29 |
Medication on admission | |||
Aspirin | 335 (99.4%) | 330 (100%) | 0.50 |
Clopidogrel | 295 (87.5%) | 263 (79.7%) | 0.01 |
Ticagrelor | 49 (14.5%) | 63 (19.1%) | 0.12 |
Prasugrel | 10 (3.0%) | 29 (8.8%) | 0.001 |
ACE inhibitor | 69 (20.5%) | 60 (18.2%) | 0.49 |
ARB | 114 (33.8%) | 94 (28.5%) | 0.16 |
β-blocker | 142 (42.1%) | 158 (47.9%) | 0.14 |
CCB | 110 (32.6%) | 116 (35.2%) | 0.51 |
Diuretics | 61 (18.1%) | 54 (16.4%) | 0.61 |
Laboratory findings | |||
Total cholesterol (mg/dL) | 174.2 ± 41.7 | 185.2 ± 49.7 | < 0.01 |
Triglyceride (mg/dL) | 144.0 ± 105.9 | 164.5 ± 175.0 | 0.08 |
HDL cholesterol (mg/dL) | 43.8 ± 11.2 | 42.9 ± 9.9 | 0.28 |
LDL cholesterol (mg/dL) | 119.6 ± 34.5 | 127.5 ± 37.1 | 0.01 |
Creatinine (mg/dL) | 1.1 ± 1.5 | 0.9 ± 0.2 | 0.06 |
Uric acid (mg/dL) | 5.5 ± 1.5 | 5.8 ± 1.6 | 0.09 |
hsCRP (mg/L) | 5.9 ± 12.6 | 7.4 ± 17.5 | 0.26 |
Fasting glucose (mmol/L) | 113.6 ± 27.8 | 116.4 ± 28.4 | 0.28 |
HbA1c (%) | 5.8 ± 0.4 | 5.8 ± 0.3 | 0.89 |