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Fig. 7 | Cardiovascular Diabetology

Fig. 7

From: Liraglutide improves lipid metabolism by enhancing cholesterol efflux associated with ABCA1 and ERK1/2 pathway

Fig. 7

Effects of liraglutide on ERK1/2 pathway in HepG2 cells with or without high glucose. Liraglutide increased p-ERK1/2 protein expression in HepG2 cells in a time-dependent manner (a). U0126, the ERK1/2 inhibitor, attenuated the increased ABCA1 expression induced by liraglutide in HepG2 cells (b). Under high glucose (HG, 50 mM) condition, U0126 reduced the increased ABCA1 expression induced by liraglutide in HepG2 cells (c). *p < 0.05, **p < 0.01,***p < 0.001, ****p < 0.0001 vs control group

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