Fig. 3From: Luseogliflozin attenuates neointimal hyperplasia after wire injury in high-fat diet-fed mice via inhibition of perivascular adipose tissue remodelingProposed mechanisms for suppression of neointimal formation by luseogliflozin. High-fat diet-induced ectopic fat deposition leads to the PVAT remodeling and infiltration of PDGF-B-expressed macrophages, which may promote the neointimal hyperplasia after wire injury. VSMC vascular smooth muscle cellsBack to article page