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Table 2 Pearson correlation coefficients between log-transformed hsCRP and HOMA-IR at baseline and follow-up in the total cohort and subgroups, adjusted for covariates

From: Temporal relationship between inflammation and insulin resistance and their joint effect on hyperglycemia: the Bogalusa Heart Study

Group Variable Baseline hsCRP Baseline HOMA-IR Follow-up hsCRP
Totala Baseline HOMA-IR 0.102   
Follow-up hsCRP 0.473 0.053  
Follow-up HOMA-IR 0.147 0.418 0.187
White/blackb Baseline HOMA-IR 0.108/0.090   
Follow-up hsCRP 0.494/0.416 0.082/− 0.014  
Follow-up HOMA-IR 0.154/0.152 0.437/0.369 0.248/0.043*
Male/femalec Baseline HOMA-IR 0.036/0.139   
Follow-up hsCRP 0.444/0.495 0.029/0.068  
Follow-up HOMA-IR 0.060/0.190 0.460/0.396 0.161/0.201
Normo/hyperd Baseline HOMA-IR 0.146/0.043   
Follow-up hsCRP 0.483/0.455 0.034/0.064  
Follow-up HOMA-IR 0.129/0.175 0.340/0.437 0.121/0.268
  1. Covariates included in the models were race, sex, age, BMI, smoking and alcohol use for the total sample and Normo/Hyper groups, with additional adjustment for follow-up years for baseline-follow-up correlations
  2. hsCRP, high-sensitivity C-reactive protein; HOMA-IR, homeostasis model assessment for insulin resistance; Normo, normoglycemia in the outcome survey; Hyper, hyperglycemia in the outcome survey
  3. aCorrelation coefficients greater than 0.087 are significant (p < 0.05)
  4. bCorrelation coefficients greater than 0.103 for whites and 0.161 for blacks are significant (p < 0.05)
  5. cCorrelation coefficients greater than 0.148 for males, and 0.108 for females are significant (p < 0.05)
  6. dCorrelation coefficients greater than 0.118 for normoglycemia, and 0.129 for hyperglycemia are significant (p < 0.05)
  7. * p < 0.05 for race difference