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Table 1 Baseline characteristics

From: Improved home BP profile with dapagliflozin is associated with amelioration of albuminuria in Japanese patients with diabetic nephropathy: the Yokohama add-on inhibitory efficacy of dapagliflozin on albuminuria in Japanese patients with type 2 diabetes study (Y-AIDA study)

Variables

Mean ± SD or %

Age (year)

65.1 ± 10.1

Sex (male/female)

65/20

Body mass index (kg/m2)

27.1 ± 4.7

Diabetes duration (year)

12.6 ± 9.2

Current smoker n (%)

17 (20.0)

Past smoker n (%)

32 (37.6)

Current drinker n (%)

43 (50.6)

Past drinker n (%)

12 (14.1)

Hypertension n (%)

74 (89.2)

Dyslipidemia n (%)

72 (86.7)

Hyperuricemia n (%)

19 (22.9)

Previous cardiovascular disease n (%)

21 (24.7)

Office blood pressure

 SBP (mmHg)

142.2 ± 18.9

 DBP (mmHg)

79.0 ± 12.0

Glucose metabolism

 Fasting plasma glucose (mg/dL)

156.9 ± 38.4

 HbA1c (%)

7.8 ± 0.7

Renal function

 Serum creatinine (mg/dL)

0.9 ± 0.2

 eGFR (mL/min/1.73 m2)

67.3 ± 17.6

 Median UACR (mg/gCr) (interquartile range)

181.5 (47.9, 638.0)

Lipid metabolism

 Total cholesterol (mg/dL)

184.4 ± 37.5

 LDL cholesterol (mg/dL)

102.0 ± 29.0

 HDL cholesterol (mg/dL)

52.7 ± 15.4

 Triglyceride (mg/dL)

173.8 ± 115.1

Antidiabetic agents

 Insulin n (%)

28 (37.8)

 Biguanides n (%)

49 (66.2)

 DPP-4 inhibitors n (%)

47 (63.5)

 Sulfonylureas n (%)

23 (31.1)

 α-Glucosidase inhibitors n (%)

17 (23.0)

 Thiazolidinediones n (%)

12 (16.2)

 Glinides n (%)

7 (9.5)

 GLP1 agonists n (%)

8 (10.8)

Antihypertensive agents

 RAS inhibitors

  Angiotensin II receptor blockers n (%)

58 (68.2)

  Angiotensin-converting enzyme inhibitors n (%)

4 (4.7)

 Calcium-channel blockers n (%)

52 (61.2)

 Diuretics n (%)

10 (11.8)

 α1-Blockers n (%)

2 (2.4)

 β-Blockers n (%)

7 (8.2)

 Spironolactone n (%)

3 (3.5)

 α2-Agonists n (%)

2 (2.4)

Antihyperlipidemic agents

 Statins n (%)

55 (64.7)

 Fibrates n (%)

4 (4.7)

 Antihyperuricemic agents n (%)

16 (18.8)

  1. Values are mean ± standard deviation (SD)
  2. SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c glycated hemoglobin, eGFR estimated glomerular filtration rate, UACR urine albumin-to-creatinine ratio, LDL low-density lipoprotein, HDL high-density lipoprotein, DPP-4 dipeptidyl peptidase 4, GLP1 glucagon-like peptide 1, RAS renin-angiotensin system