Table 2 Clinical characteristics of 1839 study subjects according to the SNP rs9267551
Characteristics | CZ | GHS | ||||||
|---|---|---|---|---|---|---|---|---|
GG | GC | CC | p | GG | GC | CC | p | |
n | 966 | 90 | 4 | 694 | 82 | 3 | ||
Males (%) | 60.8 | 54.4 | 25.0 | 0.18 | 55.0 | 57.3 | 100.0 | 0.27 |
Age (years) | 61.6 ± 11.2 | 62.1 ± 11.7 | 57.5 ± 12.7 | 0.73 | 62 ± 9 | 60 ± 9 | 68 ± 14 | 0.09 |
Age at diabetes diagnosis (years) | 53 ± 12 | 55 ± 13 | 50 ± 6 | 0.35 | 49 ± 10 | 48 ± 9 | 53 ± 13 | 0.59 |
Diabetes duration (years) | 8.6 ± 9.0 | 7.2 ± 8.8 | 8.0 ± 7.7 | 0.37 | 12.4 ± 8.8 | 11.9 ± 8.8 | 15.3 ± 5.0 | 0.74 |
BMI (kg/m2) | 31.0 ± 6.1 | 31.2 ± 6.9 | 33.7 ± 5.8 | 0.65 | 30.8 ± 5.1 | 31.7 ± 5.3 | 31.2 ± 3.7 | 0.34 |
HbA1c (%) | 7.48 ± 1.63 | 8.03 ± 1.92 | 8.16 ± 1.92 | 0.03 | 8.57 ± 1.88 | 8.68 ± 1.87 | 9.10 ± 2.38 | 0.79 |
Total cholesterol (mg/dl) | 186.9 ± 44.3 | 192.3 ± 42.0 | 213.7 ± 43.2 | 0.26 | 188.4 ± 47.7 | 182.7 ± 41.6 | 181.3 ± 68.6 | 0.56 |
HDL cholesterol (mg/dl) | 46.1 ± 13.9 | 47.3 ± 12.9 | 52.2 ± 13.8 | 0.51 | 44.9 ± 13.6 | 44.6 ± 12.2 | 43.0 ± 6.1 | 0.95 |
Triglycerides (mg/dl) | 158.1 ± 95.4 | 156.7 ± 133.6 | 105.7 ± 40.9 | 0.43 | 155.1 ± 101.5 | 149.5 ± 93.1 | 126.7 ± 92.4 | 0.70 |
Glucose-lowering therapy (%) | 65.7 | 68.9 | 50.0 | 0.66 | 84.1 | 84.1 | 100.0 | 0.75 |
Anti-hypertensive therapy (%) | 74.1 | 66.7 | 75.0 | 0.31 | 73.8 | 82.8 | 66.7 | 0.19 |
Anti-dyslipidemic therapy (%) | 41.7 | 31.1 | 0.00 | 0.03 | 47.8 | 51.2 | 66.7 | 0.68 |
Ever smoked (%) | 48.1 | 47.8 | 50.0 | 0.99 | 36.6 | 34.1 | 33.3 | 0.90 |