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Table 1 Clinical features of the study subjects

From: A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients

Characteristics CZ GHS
MI-neg MI-pos p MI-neg MI-pos p
n 883 177   595 184  
Males (%) 57.0 75.7 < 0.001 50.4 71.7 < 0.001
Age (years) 61.0 ± 11.5 64.8 ± 9.2 < 0.001 61.2 ± 8.6 64.2 ± 8.5 < 0.001
Age at diabetes diagnosis (years) 53 ± 12 54 ± 11 0.65 49 ± 10 50 ± 11 0.43
Diabetes duration (years) 7.9 ± 8.7 11.2 ± 9.7 < 0.001 11.8 ± 8.4 14.1 ± 9.6 < 0.01
BMI (kg/m2) 31.3 ± 6.4 30.1 ± 4.9 < 0.02 30.9 ± 5.2 30.8 ± 4.8 0.56
HbA1c (%) 7.49 ± 1.64 7.74 ± 1.80 0.13 8.57 ± 1.89 8.61 ± 1.81 0.81
Total cholesterol (mg/dl) 190.9 ± 43.6 170.6 ± 42.9 < 0.001 192.2 ± 46.6 173.3 ± 46.2 < 0.001
HDL cholesterol (mg/dl) 46.7 ± 14.2 44.1 ± 11.9 0.02 45.1 ± 12.5 44.1 ± 15.9 0.37
Triglycerides (mg/dl) 157.9 ± 99.9 156.4 ± 95.5 0.84 152.8 ± 100.1 159.4 ± 102.4 0.74
Glucose-lowering therapy (%) 63.3 79.1 < 0.001 83.7 85.9 0.48
Anti-hypertensive therapy (%) 70.1 90.4 < 0.001 70.8 88.6 < 0.001
Anti-dyslipidemic therapy (%) 34.7 70.6 < 0.001 40.3 73.9 < 0.001
Ever smoked (%) 44.8 64.4 < 0.001 33.9 44.0 < 0.02
  1. CZ Catanzaro Study, GHS Gargano Heart Study, MI myocardial infarction, BMI body mass index, HbA1c glycated hemoglobin