Skip to main content

Advertisement

Table 4 Multivariate linear regression analysis for ∆LVEDD after STEMI

From: Insulin resistance and dysglycemia are associated with left ventricular remodeling after myocardial infarction in non-diabetic patients

Covariates Model 1 Model 2
Coefficient (95% CI) P-value Coefficient (95% CI) P-value
Male gender − 0.009 (− 1.044 to 1.025) − 0.001 0.986 0.028 (− 1.004 to 1.061) 0.003 0.957
Age − 0.190 (− 0.453 to 0.073) − 0.066 0.157 − 0.125 (− 0.385 to 0.135) − 0.043 0.345
Smoking 0.446 (− 0.138 to 1.030) 0.067 0.134 0.366 (− 0.218 to 0.949) 0.055 0.219
Hypertension 0.351 (− 0.220 to 0.923) 0.052 0.228 0.339 (− 0.226 to 0.905) 0.050 0.239
CKD 0.886 (− 0.220 to 1.991) 0.066 0.116 0.855 (− 0.230 to 1.939) 0.063 0.122
Lymphocytes − 1.028 (− 1.563 to − 0.492) − 0.166 < 0.001 − 1.049 (− 1.581 to − 0.517) − 0.169 < 0.001
HDL cholesterol − 3.118 (− 4.722 to − 1.515) − 0.163 < 0.001 − 3.265 (− 4.878 to − 1.651) − 0.170 < 0.001
TIMI flow ≤ 2 1.215 (− 0.460 to 2.890) 0.059 0.155 1.489 (− 0.182 to 3.161) 0.072 0.081
Log cTnI 0.109 (0.007 to 0.211) 0.092 0.036 0.114 (0.012 to 0.216) 0.096 0.029
Basal LVEDD − 0.293 (− 0.359 to − 0.227) − 0.435 < 0.001 − 0.317 (− 0.384 to − 0.251) − 0.471 < 0.001
Basal LVEF − 0.145 (− 0.187 to − 0.103) − 0.344 < 0.001 − 0.145 (− 0.186 to − 0.104) − 0.343 < 0.001
HOMA-IR    < 0.001*    0.088*
 Tertile 2 vs. 1 1.196 (0.541 to 1.851) 0.170 < 0.001 − 0.361 (− 1.360 to 0.638) − 0.051 0.478
 Tertile 3 vs. 1 1.926 (1.237 to 2.614) 0.272 < 0.001 1.224 (0.095 to 2.353) 0.173 0.034
IGT − 1.337 (− 2.311 to − 0.363) − 0.185 0.007
IGT × HOMA-IR    0.001
 βint (tertile 2 vs. 1) 2.453 (1.162 to 3.744) 0.260 < 0.001
 βint (tertile 3 vs. 1) 1.925 (0.561 to 3.288) 0.197 0.006
BMI 0.760 (− 0.249 to 1.769) 0.113 0.140
BMI × HOMA-IR    0.212
 βint (tertile 2 vs. 1) 0.775 (− 0.566 to 2.117) 0.088 0.257
 βint (tertile 3 vs. 1) − 0.405 (− 1.796 to 0.985) − 0.049 0.567
  1. BMI body mass index, cTnI cardiac troponin I, CKD chronic kidney disease, HOMA-IR homeostasis model assessment-estimated insulin resistance, IGT impaired glucose tolerance, LVEDD left ventricular end-diastolic diameter, LVEF left ventricular ejection fraction, standardized coefficient, βint regression coefficient (interaction)
  2. *P for trend; P for interaction