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Table 4 Multivariate linear regression analysis for ∆LVEDD after STEMI

From: Insulin resistance and dysglycemia are associated with left ventricular remodeling after myocardial infarction in non-diabetic patients

Covariates

Model 1

Model 2

Coefficient (95% CI)

Sβ

P-value

Coefficient (95% CI)

Sβ

P-value

Male gender

− 0.009 (− 1.044 to 1.025)

− 0.001

0.986

0.028 (− 1.004 to 1.061)

0.003

0.957

Age

− 0.190 (− 0.453 to 0.073)

− 0.066

0.157

− 0.125 (− 0.385 to 0.135)

− 0.043

0.345

Smoking

0.446 (− 0.138 to 1.030)

0.067

0.134

0.366 (− 0.218 to 0.949)

0.055

0.219

Hypertension

0.351 (− 0.220 to 0.923)

0.052

0.228

0.339 (− 0.226 to 0.905)

0.050

0.239

CKD

0.886 (− 0.220 to 1.991)

0.066

0.116

0.855 (− 0.230 to 1.939)

0.063

0.122

Lymphocytes

− 1.028 (− 1.563 to − 0.492)

− 0.166

< 0.001

− 1.049 (− 1.581 to − 0.517)

− 0.169

< 0.001

HDL cholesterol

− 3.118 (− 4.722 to − 1.515)

− 0.163

< 0.001

− 3.265 (− 4.878 to − 1.651)

− 0.170

< 0.001

TIMI flow ≤ 2

1.215 (− 0.460 to 2.890)

0.059

0.155

1.489 (− 0.182 to 3.161)

0.072

0.081

Log cTnI

0.109 (0.007 to 0.211)

0.092

0.036

0.114 (0.012 to 0.216)

0.096

0.029

Basal LVEDD

− 0.293 (− 0.359 to − 0.227)

− 0.435

< 0.001

− 0.317 (− 0.384 to − 0.251)

− 0.471

< 0.001

Basal LVEF

− 0.145 (− 0.187 to − 0.103)

− 0.344

< 0.001

− 0.145 (− 0.186 to − 0.104)

− 0.343

< 0.001

HOMA-IR

  

< 0.001*

  

0.088*

 Tertile 2 vs. 1

1.196 (0.541 to 1.851)

0.170

< 0.001

− 0.361 (− 1.360 to 0.638)

− 0.051

0.478

 Tertile 3 vs. 1

1.926 (1.237 to 2.614)

0.272

< 0.001

1.224 (0.095 to 2.353)

0.173

0.034

IGT

–

–

–

− 1.337 (− 2.311 to − 0.363)

− 0.185

0.007

IGT × HOMA-IR

–

–

–

  

0.001†

 βint (tertile 2 vs. 1)

–

–

–

2.453 (1.162 to 3.744)

0.260

< 0.001

 βint (tertile 3 vs. 1)

–

–

–

1.925 (0.561 to 3.288)

0.197

0.006

BMI

–

–

–

0.760 (− 0.249 to 1.769)

0.113

0.140

BMI × HOMA-IR

–

–

–

  

0.212†

 βint (tertile 2 vs. 1)

–

–

–

0.775 (− 0.566 to 2.117)

0.088

0.257

 βint (tertile 3 vs. 1)

–

–

–

− 0.405 (− 1.796 to 0.985)

− 0.049

0.567

  1. BMI body mass index, cTnI cardiac troponin I, CKD chronic kidney disease, HOMA-IR homeostasis model assessment-estimated insulin resistance, IGT impaired glucose tolerance, LVEDD left ventricular end-diastolic diameter, LVEF left ventricular ejection fraction, Sβ standardized coefficient, βint regression coefficient (interaction)
  2. *P for trend; †P for interaction
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Cardiovascular Diabetology

ISSN: 1475-2840