Skip to main content

Table 2 Impact of lipid profile on poor collateralization in patients with and without diabetes

From: Lipoprotein (a) interactions with cholesterol-containing lipids on angiographic coronary collateralization in type 2 diabetic patients with chronic total occlusion

 

Tertiles of lipid profile

Overall (n = 1284)

Diabetes (n = 706)

Non-diabetes (n = 578)

Range

n

Poor/good

Adjusted OR (95% CI)a

P value

Poor/good

Adjusted OR (95% CI)a

P value

Poor/good

Adjusted OR (95% CI)a

P value

Lp(a)

Per tertile, mg/dL

  

1.394 (1.192–1.629)

< 0.001*

 

1.366 (1.108–1.684)

0.003*

 

1.432 (1.119–1.831)

0.004*

T1 < 12.66

426

128/298

1

–

80/147

1

–

48/151

1

–

12.66 ≤ T2 < 30.23

449

176/273

1.170 (0.861–1.591)

0.316

117/134

1.282 (0.854–1.926)

0.231

59/139

1.040 (0.640–1.688)

0.875

T3 ≥ 30.23

409

201/208

1.929 (1.413–2.633)

< 0.001

126/102

1.863 (1.227–2.830)

0.004

75/106

2.010 (1.236–3.269)

0.005

Total cholesterol

Per tertile, mmol/L

  

1.791 (1.475–2.174)

< 0.001*

 

1.814 (1.393–2.361)

< 0.001*

 

1.820 (1.358–2.440)

< 0.001*

T1 < 4.26

420

123/297

1

–

66/129

1

–

57/168

1

–

4.26 ≤ T2 < 5.35

441

170/271

1.612 (1.168–2.224)

0.004

109/129

1.993 (1.251–3.173)

0.004

61/142

1.357 (0.854–2.158)

0.196

T3 ≥ 5.35

423

212/211

3.221 (2.186–4.747)

< 0.001

148/125

3.337 (1.962–5.674)

< 0.001

64/86

3.663 (2.010–6.675)

< 0.001

LDL-C

Per tertile, mmol/L

  

1.748 (1.441–2.122)

< 0.001*

 

1.830 (1.407–2.381)

< 0.001*

 

1.699 (1.270–2.274)

< 0.001*

T1 < 2.58

401

115/286

1

–

61/138

1

–

54/148

1

–

2.58 ≤ T2 < 3.36

431

171/260

1.620 (1.164–2.255)

0.004

116/115

2.426 (1.518–3.879)

< 0.001

55/145

1.052 (0.648–1.709)

0.837

T3 ≥ 3.36

452

219/233

3.048 (2.070–4.488)

< 0.001

146/130

3.509 (2.064–5.964)

< 0.001

73/103

3.092 (1.724–5.548)

< 0.001

Non-HDL-C

Per tertile, mmol/L

  

1.828 (1.498–2.230)

< 0.001*

 

1.810 (1.386–2.364)

< 0.001*

 

1.912 (1.407–2.597)

< 0.001*

T1 < 3.30

436

131/305

1

–

71/131

1

–

60/174

1

–

3.30 ≤ T2 < 4.38

441

167/274

1.540 (1.122–2.113)

0.008

104/133

1.683 (1.073–2.639)

0.023

63/141

1.407 (0.891–2.222)

0.143

T3 ≥ 4.38

407

207/200

3.422 (2.293–5.108)

< 0.001

148/119

3.263 (1.911–5.571)

< 0.001

59/81

4.260 (2.245–8.086)

< 0.001

HDL-C

Per tertile, mmol/L

  

0.907 (0.775–1.060)

0.220*

 

0.846 (0.686–1.045)

0.121*

 

0.994 (0.780–1.267)

0.960*

T1 < 0.86

388

172/216

1

–

117/112

1

–

55/104

1

–

0.86 ≤ T2 < 1.04

437

161/276

0.809 (0.596–1.098)

0.174

101/133

0.808 (0.540–1.210)

0.302

60/143

0.834 (0.514–1.354)

0.463

T3 ≥ 1.04

459

172/287

0.820 (0.600–1.121)

0.214

105/138

0.717 (0.471–1.093)

0.122

67/149

0.975 (0.602–1.579)

0.918

Triglyceride

Per tertile, mmol/L

  

1.075 (0.914–1.266)

0.383*

 

1.092 (0.880–1.352)

0.428*

 

1.055 (0.816–1.365)

0.683*

T1 < 1.28

436

158/278

1

–

96/122

1

–

62/156

1

–

1.28 ≤ T2 < 1.84

448

175/273

1.109 (0.822–1.497)

0.498

99/135

0.947 (0.625–1.434)

0.796

76/138

1.311 (0.840–2.046)

0.232

T3 ≥ 1.84

400

172/228

1.155 (0.833–1.600)

0.387

128/126

1.183 (0.771–1.817)

0.442

44/102

1.072 (0.633–1.814)

0.796

  1. CI confidence interval, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Lp(a) lipoprotein a, OR odds ratio
  2. * P for trend for tertiles of lipid profile
  3. aMultiple adjustment for gender, age, body mass index, hypertension, diabetes, dyslipidemia, smoking, prior myocardial infarction, multi-vessel disease, glomerular filtration rate, log-transferred high-sensitivity C reactive protein and left ventricular ejection fraction