Table 1 Characteristics of cases and matched controls
Variables | Cases (N = 1150) | Controls (N = 3450) | Crude OR [95% CI] | p |
|---|---|---|---|---|
Sex, male | 578 (50.3) | 1734 (50.3) | – | |
Age | 70–74 [65–69; 75–79] | 70–74 [65–69; 75–79] | – | |
Hypertension | 1039 (90.3) | 3005 (87.1) | 1.40 [1.12–1.75] | 0.003 |
Atrial fibrillation | 184 (16.0) | 398 (11.5) | 1.49 [1.22–1.80] | < 0.001 |
Prior myocardial infarction | 140 (12.2) | 358 (10.4) | 1.20 [0.97–1.48] | 0.088 |
Use of medications | ||||
Antithromboticsa | 713 (62.0) | 2391 (69.3) | 0.68 [0.58–0.79] | < 0.001 |
Statins | 276 (24.0) | 1156 (33.5) | 0.61 [0.52–0.71] | < 0.001 |
Sulfonylurea | 411 (35.7) | 1233 (35.7) | – | |
Biguanide | 379 (33.0) | 1137 (33.0) | – | |
Dipeptidyl peptidase 4 inhibitor | 34 (3.0) | 102 (3.0) | – | |
Alpha-glucosidase inhibitor | 86 (7.5) | 258 (7.5) | ||
Pioglitazone | 11 (1.0) | 74 (2.1) | 0.44 [0.23–0.83] | 0.012 |
Insulin | 347 (30.2) | 1041 (30.2) | – | |