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Table 1 Baseline participant characteristic by Hp phenotypes

From: Association of haptoglobin phenotype with incident acute myocardial infarction in Chinese patients with type 2 diabetes

Variable

SMART2D

DN

Hp 1-1 (N = 110)

Hp 2-1 (N = 449)

Hp 2-2 (N = 475)

P value

Hp 1-1 (N = 133)

Hp 2-1 (N = 561)

Hp 2-2 (N = 596)

P value

Age (years)

58.13 ± 10.16

59.05 ± 11.64

58.73 ± 11.51

0.737

58.54 ± 12.94

57.70 ± 12.64

59.10 ± 12.22

0.163

Female (%)

40.9

47.2

45.5

0.486

41.4

34.8

39.6

0.154

Smoking history (%)

–

–

–

0.788

–

–

–

0.932

Current

8.2

7.8

9.1

–

14.0

13.8

11.5

–

Ex

9.1

7.6

7.8

–

15.5

16.4

15.8

–

Never

82.7

84.6

83.1

–

70.5

69.9

72.7

–

BMI (kg/m2)

26.15 ± 4.12

26.75 ± 5.00

26.27 ± 4.47

0.231

26.18 ± 4.68

26.07 ± 5.26

26.21 ± 4.41

0.895

HbA1c (%)

8.14 ± 1.69

7.61 ± 1.43

7.81 ± 1.60

0.018

8.06 ± 1.82

8.31 ± 1.96

8.13 ± 1.81

0.178

Diabetes duration (years)

11.12 ± 7.63

12.15 ± 9.88

12.60 ± 10.06

0.346

12.24 ± 10.00

11.83 ± 8.90

11.92 ± 9.05

0.894

SBP (mm Hg)

140.35 ± 17.40

143.05 ± 18.61

141.62 ± 20.47

0.323

135.81 ± 19.60

134.46 ± 18.78

137.16 ± 20.20

0.067

DBP (mm Hg)

77.64 ± 8.35

78.99 ± 9.45

78.53 ± 9.67

0.383

77.53 ± 11.51

76.53 ± 10.29

76.76 ± 10.98

0.634

TC (mmol/L)

4.42 ± 1.05

4.40 ± 0.89

4.41 ± 0.95

0.954

4.60 ± 0.96

4.63 ± 1.16

4.63 ± 1.11

0.947

HDL (mmol/L)

1.36 ± 0.36

1.32 ± 0.36

1.34 ± 0.36

0.419

1.33 ± 0.40

1.28 ± 0.36

1.29 ± 0.38

0.375

LDL (mmol/L)

2.73 ± 0.89

2.70 ± 0.79

2.72 ± 0.81

0.942

2.78 ± 0.84

2.73 ± 0.86

2.74 ± 0.79

0.775

TG (mmol/L)

1.65 ± 0.98

1.73 ± 1.32

1.68 ± 1.75

0.829

1.70 ± 1.05

1.93 ± 1.44

1.80 ± 1.21

0.116

uACR (mg/g)

24.0 (7.0–103.0)

21.0 (5.8–132.3)

25.0 (7.0–116.5)

0.847

39.4 (12.0–109.5)

44.0 (11.0–239.0)

37.0 (10.0–228)

0.322

eGFR (ml/min/1.73 m2)

84.59 ± 28.07

83.16 ± 28.61

84.82 ± 26.92

0.649

75.52 ± 27.86

78.69 ± 29.90

77.30 ± 29.01

0.467

Medication (%)

        

Insulin

22.7

27.4

24.8

0.505

26.3

34.8

30.4

0.097

RAS antagonist

55.5

62.1

58.9

0.364

60.2

64.5

46.6

0.589

Lipid lowering

80.0

82.0

83.8

0.573

71.8

73.7

74.9

0.731

  1. Statistically significant are in italics (P values < 0.05)
  2. Data are presented as frequencies (%) for categorical variables and as the mean ± SD for continuous, normally distributed variables
  3. BMI body mass index, DBP diastolic blood pressure, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, RAS renin–angiotensin system, SBP systolic blood pressure, TC total cholesterol, TG triglycerides, uACR urine albumin-to-creatinine ratio, eGFR estimated glomerular filtration rate
  4. P-values are for the difference among the Hp phenotype within the study cohorts