Variable | SMART2D | DN | ||||||
---|---|---|---|---|---|---|---|---|
Hp 1-1 (N = 110) | Hp 2-1 (N = 449) | Hp 2-2 (N = 475) | P value | Hp 1-1 (N = 133) | Hp 2-1 (N = 561) | Hp 2-2 (N = 596) | P value | |
Age (years) | 58.13 ± 10.16 | 59.05 ± 11.64 | 58.73 ± 11.51 | 0.737 | 58.54 ± 12.94 | 57.70 ± 12.64 | 59.10 ± 12.22 | 0.163 |
Female (%) | 40.9 | 47.2 | 45.5 | 0.486 | 41.4 | 34.8 | 39.6 | 0.154 |
Smoking history (%) | – | – | – | 0.788 | – | – | – | 0.932 |
Current | 8.2 | 7.8 | 9.1 | – | 14.0 | 13.8 | 11.5 | – |
Ex | 9.1 | 7.6 | 7.8 | – | 15.5 | 16.4 | 15.8 | – |
Never | 82.7 | 84.6 | 83.1 | – | 70.5 | 69.9 | 72.7 | – |
BMI (kg/m2) | 26.15 ± 4.12 | 26.75 ± 5.00 | 26.27 ± 4.47 | 0.231 | 26.18 ± 4.68 | 26.07 ± 5.26 | 26.21 ± 4.41 | 0.895 |
HbA1c (%) | 8.14 ± 1.69 | 7.61 ± 1.43 | 7.81 ± 1.60 | 0.018 | 8.06 ± 1.82 | 8.31 ± 1.96 | 8.13 ± 1.81 | 0.178 |
Diabetes duration (years) | 11.12 ± 7.63 | 12.15 ± 9.88 | 12.60 ± 10.06 | 0.346 | 12.24 ± 10.00 | 11.83 ± 8.90 | 11.92 ± 9.05 | 0.894 |
SBP (mm Hg) | 140.35 ± 17.40 | 143.05 ± 18.61 | 141.62 ± 20.47 | 0.323 | 135.81 ± 19.60 | 134.46 ± 18.78 | 137.16 ± 20.20 | 0.067 |
DBP (mm Hg) | 77.64 ± 8.35 | 78.99 ± 9.45 | 78.53 ± 9.67 | 0.383 | 77.53 ± 11.51 | 76.53 ± 10.29 | 76.76 ± 10.98 | 0.634 |
TC (mmol/L) | 4.42 ± 1.05 | 4.40 ± 0.89 | 4.41 ± 0.95 | 0.954 | 4.60 ± 0.96 | 4.63 ± 1.16 | 4.63 ± 1.11 | 0.947 |
HDL (mmol/L) | 1.36 ± 0.36 | 1.32 ± 0.36 | 1.34 ± 0.36 | 0.419 | 1.33 ± 0.40 | 1.28 ± 0.36 | 1.29 ± 0.38 | 0.375 |
LDL (mmol/L) | 2.73 ± 0.89 | 2.70 ± 0.79 | 2.72 ± 0.81 | 0.942 | 2.78 ± 0.84 | 2.73 ± 0.86 | 2.74 ± 0.79 | 0.775 |
TG (mmol/L) | 1.65 ± 0.98 | 1.73 ± 1.32 | 1.68 ± 1.75 | 0.829 | 1.70 ± 1.05 | 1.93 ± 1.44 | 1.80 ± 1.21 | 0.116 |
uACR (mg/g) | 24.0 (7.0–103.0) | 21.0 (5.8–132.3) | 25.0 (7.0–116.5) | 0.847 | 39.4 (12.0–109.5) | 44.0 (11.0–239.0) | 37.0 (10.0–228) | 0.322 |
eGFR (ml/min/1.73 m2) | 84.59 ± 28.07 | 83.16 ± 28.61 | 84.82 ± 26.92 | 0.649 | 75.52 ± 27.86 | 78.69 ± 29.90 | 77.30 ± 29.01 | 0.467 |
Medication (%) | Â | Â | Â | Â | Â | Â | Â | Â |
Insulin | 22.7 | 27.4 | 24.8 | 0.505 | 26.3 | 34.8 | 30.4 | 0.097 |
RAS antagonist | 55.5 | 62.1 | 58.9 | 0.364 | 60.2 | 64.5 | 46.6 | 0.589 |
Lipid lowering | 80.0 | 82.0 | 83.8 | 0.573 | 71.8 | 73.7 | 74.9 | 0.731 |