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Table 1 Characteristics of study population (mean ± SD/median [IQR])

From: Cardiovascular organ damage in type 2 diabetes mellitus: the role of lipids and inflammation

 

T2DM patients

nonT2DM subjects

 

Gender (M:F)

148:43

66:28

0.20

Age (years)

65 ± 7

62 ± 8

< 0.0001

T2DM duration (years)

6 [11]

  

Body weight (kg)

84 ± 15

79 ± 12

< 0.005

BMI (kg/m2)

29.0 ± 4.5

27.2 ± 3.6

< 0.001

Waist circumference (cm)

106 ± 12

98 ± 11

< 0.0001

Systolic BP/diastolic BP (mmHg)

135 ± 19/77 ± 10

128 ± 15/78 ± 10

< 0.05a

Heart rate (bpm)

66 ± 11

60 ± 9

< 0.0001

LDL-cholesterol (mmol/L)

2.67 ± 0.85

2.86 ± 0.94

0.09

HDL-cholesterol (mmol/L)

1.27 ± 0.28

1.35 ± 0.35

< 0.05

Triglycerides (mmol/L)

1.32 [0.82]

1.25 [0.61]

0.08

Fasting glucose (mmol/L)

7.4 ± 1.8

4.9 ± 0.6

< 0.0001

HbA1c (%)

7.0 [1.4]

5.7 [0.4]

< 0.0001

hsCRP (mg/dL)

0.15 [0.26]

0.17 [0.19]

0.40

IL-6 (AU)

36 [25]

29 [25]

< 0.01

IL-18 (AU)

1314 [637]

1140 [557]

0.005

MMP-12 (AU)

139 [96]

98 [58]

< 0.0001

BP-lowering therapy (%)

73.3

52.1

< 0.0005

Lipid-lowering therapy (%)

62.8

50.0

< 0.05

Current smoking (%)

31.1

34.0

0.57

CV events (%)

49.2

40.4

0.44a

cIMT (μm)

782 ± 129

668 ± 139

< 0.01a

cIMT > 90th percentile (%)

33.5

18.1

0.005

IADiam (mm)

8.52 ± 0.91

8.05 ± 0.92

< 0.005a

ccaWS (m/s)

8.9 ± 1.8

7.9 ± 1.5

0.001a

cfPWV (m/s)

11.4 ± 2.4

9.3 ± 2.0

< 0.0001a

cfPWV > 90th percentile (%)

27.2

4.3

< 0.0001

LV mass (g)

225 ± 54

199 ± 52

< 0.0005

LV hypertrophy (%)

51.8

29.8

< 0.001

s′ velocity (cm/s)

8.6 ± 1.3

8.8 ± 1.6

0.28

e′ velocity (cm/s)

8.7 ± 1.4

9.7 ± 2.0

< 0.0005a

Stroke volume (mL)

81 ± 16

70 ± 19

< 0.0001

End-systolic wall stress (*103 dynes/cm2)

72 ± 24

69 ± 29

0.44

  1. aAfter adjustment for age