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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients

Fig. 4

Increased EETs degradation by sEH in type 2 diabetes. Ratio of plasma 14,15-dihydroxyeicosatrienoic acid-to-14,15-epoxyeicosatrienoic acid (14,15-DHET/14,15-EET) (a), sEH activity (b), mRNA (c) and protein expression (d) in peripheral blood mononuclear cells in healthy, hypertensive (HT), type 2 diabetic (T2D) and hypertensive type 2 diabetic (HT + T2D) subjects. β2M: beta2-microglobulin. Mean values ± SEM are shown. *P < 0.05, **P < 0.01

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