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Table 2 Hazard ratios and 95% confidence intervals of all-cause mortality, myocardial infarction and stroke by the weight-changes for 2 years after diagnosis of diabetes mellitus

From: Weight change and mortality and cardiovascular outcomes in patients with new-onset diabetes mellitus: a nationwide cohort study

Weight change (%) Events (n) Incidence rate (per 1000 person-years) Model 1 Model 2 Model 3
Myocardial infarction
 ≥ − 10% 72 3.05 1.06 (0.84, 1.35) 1.05 (0.83,1.34) 1.08 (0.85, 1.38)
 − 10 ~ − 5% 265 3.04 1.06 (0.93, 1.22) 1.07 (0.93,1.22) 1.10 (0.96, 1.27)
 − 5 ~ 5% 1188 2.84 1 (ref.) 1 (ref.) 1 (ref.)
 5 ~ 10% 174 2.95 1.06 (0.91, 1.25) 1.05 (0.90,1.23) 1.04 (0.88, 1.22)
 ≥ 10% 68 3.09 1.13 (0.89, 1.45) 1.11 (0.87,1.42) 1.07 (0.84, 1.38)
Stroke
 ≥ − 10% 93 3.95 1.07 (0.86, 1.32) 1.05 (0.85,1.30) 1.08 (0.87, 1.34)
 − 10 ~ − 5% 278 3.19 0.92 (0.81, 1.05) 0.92 (0.81,1.05) 0.97 (0.85, 1.11)
 − 5 ~ 5% 1375 3.29 1 (ref.) 1 (ref.) 1 (ref.)
 5 ~ 10% 207 3.51 1.11 (0.96, 1.28) 1.10 (0.95,1.28) 1.08 (0.93, 1.25)
 ≥ 10% 107 4.89 1.57 (1.29, 1.91) 1.51 (1.23,1.84) 1.47 (1.20, 1.79)
All-cause mortality
 ≥ − 10% 224 9.43 2.07 (1.80, 2.38) 1.86 (1.61,2.14) 1.83 (1.59, 2.12)
 − 10 ~ − 5% 523 5.96 1.34 (1.22, 1.48) 1.28 (1.16,1.41) 1.27 (1.15, 1.41)
 − 5 ~ 5% 1862 4.43 1 (ref.) 1 (ref.) 1 (ref.)
 5 ~ 10% 343 5.78 1.30 (1.16, 1.46) 1.27 (1.13,1.43) 1.26 (1.12, 1.41)
 ≥ 10% 161 7.28 1.65 (1.40, 1.94) 1.61 (1.37,1.89) 1.57 (1.33, 1.85)
  1. Model 1: adjusted for age and sex
  2. Model 2: adjusted for model 1 plus alcohol drinking, smoking, regular exercise and income status
  3. Model 3: adjusted for model 2 plus baseline fasting glucose levels, dyslipidemia, hypertension, waist circumferences, use of insulin and estimated glomerular filtration rate