Table 2 Hazard ratios and 95% confidence intervals of all-cause mortality, myocardial infarction and stroke by the weight-changes for 2 years after diagnosis of diabetes mellitus
Weight change (%) | Events (n) | Incidence rate (per 1000 person-years) | Model 1 | Model 2 | Model 3 |
|---|---|---|---|---|---|
Myocardial infarction | |||||
 ≥ − 10% | 72 | 3.05 | 1.06 (0.84, 1.35) | 1.05 (0.83,1.34) | 1.08 (0.85, 1.38) |
 − 10 ~ − 5% | 265 | 3.04 | 1.06 (0.93, 1.22) | 1.07 (0.93,1.22) | 1.10 (0.96, 1.27) |
 − 5 ~ 5% | 1188 | 2.84 | 1 (ref.) | 1 (ref.) | 1 (ref.) |
 5 ~ 10% | 174 | 2.95 | 1.06 (0.91, 1.25) | 1.05 (0.90,1.23) | 1.04 (0.88, 1.22) |
 ≥ 10% | 68 | 3.09 | 1.13 (0.89, 1.45) | 1.11 (0.87,1.42) | 1.07 (0.84, 1.38) |
Stroke | |||||
 ≥ − 10% | 93 | 3.95 | 1.07 (0.86, 1.32) | 1.05 (0.85,1.30) | 1.08 (0.87, 1.34) |
 − 10 ~ − 5% | 278 | 3.19 | 0.92 (0.81, 1.05) | 0.92 (0.81,1.05) | 0.97 (0.85, 1.11) |
 − 5 ~ 5% | 1375 | 3.29 | 1 (ref.) | 1 (ref.) | 1 (ref.) |
 5 ~ 10% | 207 | 3.51 | 1.11 (0.96, 1.28) | 1.10 (0.95,1.28) | 1.08 (0.93, 1.25) |
 ≥ 10% | 107 | 4.89 | 1.57 (1.29, 1.91) | 1.51 (1.23,1.84) | 1.47 (1.20, 1.79) |
All-cause mortality | |||||
 ≥ − 10% | 224 | 9.43 | 2.07 (1.80, 2.38) | 1.86 (1.61,2.14) | 1.83 (1.59, 2.12) |
 − 10 ~ − 5% | 523 | 5.96 | 1.34 (1.22, 1.48) | 1.28 (1.16,1.41) | 1.27 (1.15, 1.41) |
 − 5 ~ 5% | 1862 | 4.43 | 1 (ref.) | 1 (ref.) | 1 (ref.) |
 5 ~ 10% | 343 | 5.78 | 1.30 (1.16, 1.46) | 1.27 (1.13,1.43) | 1.26 (1.12, 1.41) |
 ≥ 10% | 161 | 7.28 | 1.65 (1.40, 1.94) | 1.61 (1.37,1.89) | 1.57 (1.33, 1.85) |