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Table 4 Patient characteristics by comorbidity (overall study population)

From: Patient and disease characteristics of type-2 diabetes patients with or without chronic kidney disease: an analysis of the German DPV and DIVE databases

  Prior stroke Retinopathy CAD CKDb Diabetic foot complications PAD
(n = 26,270) (n = 18,036) (n = 30,748) (n = 171,930) (n = 38,765) (n = 56,741)
Healthcare provider
 Office based in % 25.3 36.9 30.5 31.5 49.5 44.3
 Hospital based in % 74.7 63.1 69.5 68.5 50.5 55.7
Age in years 75.1 (67.8; 81.0) 71.1 (63.1; 78.0) 73.2 (65.4; 79.6) 74.5 (66.1; 80.7) 72.8 (64.3; 79.2) 73.9 (65.9; 80.1)
 < 65 years 18.1 29.9 23.7 22.4 26.7 22.6
 ≥ 65 years 81.9 70.1 76.3 77.6 73.3 77.4
Female gender in % 46.0 46.2 36.4 52.4 39.3 42.0
Weight in kg 82.0 (71.9; 94.8) 86.5 (75.0; 100.0) 85.0 (74.3; 98.0) 84.7 (73.0; 98.3) 88.0 (75.4; 103.0) 85.0 (74.0; 99.4)
Body mass index in kg/m2 29.0 (25.6; 32.9) 30.5 (26.8; 34.8) 29.4 (26.2; 33.5) 29.9 (26.3; 34.4) 30.1 (26.3; 34.6) 29.7 (26.1; 34.1)
Blood pressure
 Systolic BP in mmHg 135.0 (123.0; 146.5) 135.0 (125.0; 147.5) 130.0 (120.0; 140.0) 132.5 (120.0; 145.0) 134.0 (125.0; 145.0) 134.0 (123.0; 145.0)
  Systolic BP ≥ 140 mmHg in % 44.5 45.9 36.1 41.7 41.3 41.2
 Diastolic BP in mmHg 77.5 (70.0; 80.0) 79.0 (70.0; 80.0) 75.0 (70.0; 80.0) 78.0 (70.0; 80.0) 77.0 (70.0; 80.0) 75.5 (70.0; 80.0)
  Diastolic BP ≥ 90 mmHg in % 12.4 12.2 9.2 12.2 9.9 10.0
 AntiHT drug treatment in % 72.5 71.0 75.4 62.6 64.0 70.0
 Hypertensiona in % 85.3 84.2 85.2 79.4 79.5 82.5
Dyslipidemia in % 90.2 87.5 91.4 88.4 85.4 87.4
 LDL-C in mg/dL 104.0 (79.0; 133.0) 104.4 (80.0; 132.0) 96.0 (73.5; 123.7) 105.0 (79.3; 135.0) 104.0 (80.0; 130.0) 104.0 (79.3; 131.5)
 TC in mg/dL 177.9 (147.0; 211.5) 182 (152.7; 214.0) 168.0 (140.0; 201.1) 181.7 (150.8; 216.0) 176.0 (147.0; 208.0) 177.9 (149.0; 211.0)
 TG in mg/dL 151.0 (109.0; 215.0) 152.0 (109.0; 217.0) 151.0 (109.0; 218.0) 157.9 (113.0; 228.1) 148.9 (105.3; 210.5) 150.6 (108.0; 215.2)
 HDL-C in men in mg/dL 40.0 (34.0; 49.0) 42.0 (35.0; 50.3) 39.5 (33.0; 48.0) 40.0 (33.0, 48.5) 41.0 (34.6; 50.3) 41.3 (34.5; 50.3)
 HDL-C in women in mg/dL 46.0 (37.0; 56.1) 47.0 (38.7; 58.0) 45.0 (37.0; 55.5) 46.4 (37.5; 57.0) 48.0 (39.0; 58.5) 47.0 (38.7; 58.0)
Diabetes
 Diabetes duration in years 10.5 (5.2; 17.3) 16.1 (9.9; 23.7) 10.6 (5.1; 18.0) 10.3 (4.9; 17.2) 13.2 (7.5; 20.3) 12.0 (6.5; 19.4)
  0–5 years in % 24.1 10.6 24.8 25.5 15.9 18.9
  6–10 years in % 22.4 14.9 21.5 22.2 19.6 21.4
  > 10 years in % 53.4 74.5 53.7 52.3 64.5 59.7
 HbA1c in % 7.1 (6.3; 8.2) 7.5 (6.6; 8.6) 7.1 (6.3; 8.2) 7.1 (6.3; 8.3) 7.1 (6.3; 8.1) 7.0 (6.3; 8.1)
 HbA1c < 6.5% in % 31.7 21.7 32.2 30.5 30.7 32.5
 HbA1c < 7.0% in % 47.6 36.7 48.0 45.8 47.6 48.9
Kidney parameters
 Potassium in mmol/L 4.3 (3.9; 4.6) 4.4 (4.0; 4.7) 4.3 (4.0; 4.7) 4.3 (3.9; 4.7) 4.4 (4.1; 4.8) 4.3(4.0; 4.7)
  ≤ 4.8 mmol/L in % 85.4 81.9 83.2 81.8 79.9 81.6
  > 4.8–≤ 5.5 mmol/L in % 11.9 15.6 14.1 14.6 16.9 15.1
  > 5.5– ≤ 6.0 mmol/L in % 1.7 1.7 1.8 2.3 2.3 2.2
   > 6.0 mmol/L in % 1.1 0.7 0.9 1.3 0.9 1.0
 Urinary albumin in mg/g
  Normal (< 30 mg/g) in % 70.0 66.7 71.1 48.8 66.3 65.9
  Micro (≥ 30–300 mg/g) in % 23.1 24.9 22.5 40.8 26.4 26.5
  Macro (> 300 mg/g) in % 6.9 8.4 6.4 10.4 7.3 7.6
 Creatinine in mg/dL 1.1 (0.9; 1.4) 1.0 (0.8; 1.4) 1.1 (0.9; 1.4) 1.3 (1.0; 1.6) 1.1 (0.9 1.4) 1.1 (0.9; 1.5)
 eGFR mL/min/1.73 m2 59.4 (42.4; 76.8) 60.9 (42.8; 79.8) 59.6 (42.5; 76.0) 48.9 (36.3; 59.0) 61.5 (43.1; 81.1) 59.2 (41.7; 77.7)
  < 15 2.0 2.1 1.7 3.0 2.2 2.2
  15 to < 30 in % 8.8 9.3 9.0 12.6 8.5 9.4
  30 to < 45 in  % 17.8 16.6 17.6 25.9 16.7 17.9
  45 to < 60 in % 22.5 20.7 22.3 36.6 20.4 21.7
  60 to < 90 in % 35.9 35.7 37.3 14.1 36.1 35.4
  ≥ 90 in % 13.1 15.7 12.1 7.9 16.2 13.4
  1. Median (Q1; Q3) or percent (%)
  2. Patients with multiple comorbidities possible
  3. AntiHT antihypertensive, BP blood pressure, CAD coronary artery disease, CKD chronic kidney disease, eGFR estimated glomerular filtration rate, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, PAD peripheral artery disease, TC total cholesterol, TG triglycerides
  4. aDefined as either systolic BP ≥ 140 mmHg OR diastolic BP ≥ 90 mmHg OR on antihypertensive drug treatment
  5. bDefined as eGFR < 60 mL/min/1.73 m2 OR eGFR ≥ 60 mL/min/1.73 m2 and albuminuria (≥ 30 mg/g)