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Fig. 5 | Cardiovascular Diabetology

Fig. 5

From: Pioglitazone strengthen therapeutic effect of adipose-derived regenerative cells against ischemic cardiomyopathy through enhanced expression of adiponectin and modulation of macrophage phenotype

Fig. 5

Cardiac function and survival rate after transplantation. a ADRCs grafts improved left ventricular ejection fraction after implantation. b Left ventricular anterior wall thickness was preserved in A, AP and Si groups. c, d In A, AP and Si groups, the left ventricular end-systolic dimension was significantly smaller than that in the C group. However, the end-diastolic diameter was almost the same among the groups. e, f Representative M-mode pictures of echocardiography of control and ADRC groups. Arrows indicate anterior wall of the left ventricle. g The ADRC transplantation groups showed significantly better survival than did group C. There was no significant difference among the A, AP, and Si groups. Multiple comparisons made by one-way ANOVA. *P < 0.05 versus C group, **P < 0.05 versus A group, †P < 0.05 versus Si group, n = 8–10 per group

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