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Table 3 Characteristics of the study population, according to the occurrence or not of overall new PCI (for restenosis and de novo IHD) (n = 54)

From: Adiponectin and insulin resistance are related to restenosis and overall new PCI in subjects with normal glucose tolerance: the prospective AIRE Study

Parameter Univariate analysis Multivariate analysis
Overall new PCI p OR [95% CI] p
Yes (n = 8) No (n = 46)
Age (years), median [IQR] 59.5 [58–60.7] 60.5 [57.7–63] 0.590   
Sex, no. (%)    0.380   
 M 6 (75) 40 (87)    
 F 2 (25) 6 (13)    
BMI, kg/m2, median [IQR] 26.7 [24.8–28.8] 27 [25.8–28] 1.000   
Blood pressure (mmHg), median [IQR]
 Systolic 125 [120–130] 130 [120–136.2] 0.296   
 Diastolic 80 [72.5–80] 80 [70–80] 0.574   
Hypertension, no. (%) 1 (14) 14 (30) 0.296   
Smoke, no. (%) 7 (88) 36 (78) 0.549   
Cholesterol (mg/dL), median [IQR]
Total 173.5 [147.5–209.7] 172.5 [146.2–189] 0.658   
 HDL 44 [34.2–64.5] 42 [35–51] 0.590   
 LDL 107.5 [86–123.7] 105 [70.2–119.7] 0.765   
Triglycerides (mg/dL), median [IQR] 127.5 [117.2–157.7] 127 [102.7–151.5] 0.495   
Glycemia (mg/dL), median [IQR]
 Baseline 95.5 [86.2–97.7] 86.5 [79.7–89.2] 0.015 0.643 [0.389–1.064] 0.086
 2 h 132 [116–136.7] 102.5 [93–121.2]    
Glycated hemoglobin (%), median [IQR] 5.6 [5.5–5.7] 5.2 [5–5.4] 0.001   
Insulin (µU/mL), median [IQR] 9.8 [9.1–10.1] 3.5 [2.8–4.3] 0.000 0.008 [0.000–1.183] 0.058
HOMA IR, median [IQR] 2.23 [2.1–2.5] 0.74 [0.57–0.94] 0.000 1.5*1011 [2.593–8.68 * 1021] 0.042
Creatinine (mg/dL), median [IQR] 1 [0.85–1.1] 1 [0.87–1.1] 0.971   
Hemoglobin (mg/dL), median [IQR] 14.2 [13.2–14.8] 14.3 [13.3–15.3] 0.495   
Adiponectin (µg/mL), median [IQR] 8 [6.5–8.7] 12 [10–14] 0.000 0.206 [0.053–0.796] 0.022
Resistin (ng/mL), median [IQR] 13 [6–15] 6 [4–8] 0.013   
TNF-alpha (ng/mL), median [IQR] 13 [7.5–20.7] 8 [7–10] 0.073   
Follow-up duration (months), median [IQR] 31 [25.7–33.7] 29 [13.5–34] 0.558   
Death, no. (%)
 Cardiovascular/other causes 0 (−)/− 0 (−)/1 (2) 0.674