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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart

Fig. 4

Effect of empagliflozin on Nrf2/ARE and TGF-β/SMAD pathway in vivo. a Western blot analysis for the expression of TGF-β/SMAD pathway was performed on protein isolated from the hearts of the three groups. b Western blot analysis for the expression of Nrf2/ARE pathway of heart tissue in mice. c The relative protein levels were calculated and Lamin B was used as an internal control. d The relative protein levels were calculated and β-actin was used as an internal control. Data are expressed as the mean ± SD. *P < 0.05 vs. Con; #P < 0.05 vs. DM

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