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Table 7 Comparison between patients with and without statin treatment

From: Associations between epicardial adipose tissue, subclinical atherosclerosis and high-density lipoprotein composition in type 1 diabetes

  With statins treatment (n = 31) Without statins treatment (n = 41) P-value
HbA1c (%) 7.9 ± 1.1 7.03 ± 0.9 0.021
Age (years) 51.55 ± 8.4 43.8 ± 7.4 < 0.001
iEAT (cm3/m2) 47.9 ± 27.2 34.9 ± 9.0 0.013
Lesions (any degree of stenosis) 21 (29.2%) 15 (20.8%) 0.017
Lipid profile
 Total cholesterol (mmol/l) 4.6 ± 0.6 4.9 ± 0.8 0.083
 Triglycerides (mmol/l)* 1.0 ± 0.6 1.05 ± 1.1 0.320
 LDL cholesterol (mmol/l) 2.7 ± 0.5 2.9 ± 0.6 0.067
 HDL cholesterol (mmol/l) 1.5 ± 0.3 1.5 ± 0.3 0.796
 Lp(a) (mg/l)* 445 ± 618.8 207 ± 218.1 0.148
HDL-associated parameters
 HDL 2 (%) 54.3 ± 17.6 53.8 ± 20.7 0.912
 HDL 3 (%) 45.6 ± 17.6 47.8 ± 24.9 0.671
 PON1 (μmol/min·ml) 316.1 ± 77.7 291.4 ± 76.5 0.191
 Total Lp-PLA2 (µmol/min·ml)* 18.2 ± 5.1 19.9 ± 4.8 0.180
 Lp-PLA2 in HDL (µmol/min·ml)* 5.6 ± 1.4 5.8 ± 1.7 0.491
 Lp-PLA2 in HDL (%) * 32.3 ± 9.7 29.9 ± 9.6 0.178
 HDL total cholesterol (%) 17.6 ± 1.7 17.5 ± 1.8 0.911
 HDL esterified cholesterol (%) 14.3 ± 1.5 14.2 ± 1.4 0.795
 HDL triglycerides (%) 3.8 ± 1.4 3.7 ± 1.6 0.882
 HDL phospholipids (%) 28.3 ± 2.3 29 ± 1.9 0.206
 HDL apoA-I (%) 38.1 ± 2.2 38 ± 1.3 0.811
 HDL apoA-II (%) 9.9 ± 1.5 9.4 ± 1.4 0.141
 HDL apoE (%) 0.5 ± 0.4 0.6 ± 0.2 0.518
 HDL apoC-III (%) 1.7 ± 0.6 1.7 ± 0.6 0.703
  1. Italic values indicate significance of p value (p < 0.05)
  2. * Indicates non-parametric values