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Table 7 Comparison between patients with and without statin treatment

From: Associations between epicardial adipose tissue, subclinical atherosclerosis and high-density lipoprotein composition in type 1 diabetes

 

With statins treatment (n = 31)

Without statins treatment (n = 41)

P-value

HbA1c (%)

7.9 ± 1.1

7.03 ± 0.9

0.021

Age (years)

51.55 ± 8.4

43.8 ± 7.4

< 0.001

iEAT (cm3/m2)

47.9 ± 27.2

34.9 ± 9.0

0.013

Lesions (any degree of stenosis)

21 (29.2%)

15 (20.8%)

0.017

Lipid profile

 Total cholesterol (mmol/l)

4.6 ± 0.6

4.9 ± 0.8

0.083

 Triglycerides (mmol/l)*

1.0 ± 0.6

1.05 ± 1.1

0.320

 LDL cholesterol (mmol/l)

2.7 ± 0.5

2.9 ± 0.6

0.067

 HDL cholesterol (mmol/l)

1.5 ± 0.3

1.5 ± 0.3

0.796

 Lp(a) (mg/l)*

445 ± 618.8

207 ± 218.1

0.148

HDL-associated parameters

 HDL 2 (%)

54.3 ± 17.6

53.8 ± 20.7

0.912

 HDL 3 (%)

45.6 ± 17.6

47.8 ± 24.9

0.671

 PON1 (μmol/min·ml)

316.1 ± 77.7

291.4 ± 76.5

0.191

 Total Lp-PLA2 (µmol/min·ml)*

18.2 ± 5.1

19.9 ± 4.8

0.180

 Lp-PLA2 in HDL (µmol/min·ml)*

5.6 ± 1.4

5.8 ± 1.7

0.491

 Lp-PLA2 in HDL (%) *

32.3 ± 9.7

29.9 ± 9.6

0.178

 HDL total cholesterol (%)

17.6 ± 1.7

17.5 ± 1.8

0.911

 HDL esterified cholesterol (%)

14.3 ± 1.5

14.2 ± 1.4

0.795

 HDL triglycerides (%)

3.8 ± 1.4

3.7 ± 1.6

0.882

 HDL phospholipids (%)

28.3 ± 2.3

29 ± 1.9

0.206

 HDL apoA-I (%)

38.1 ± 2.2

38 ± 1.3

0.811

 HDL apoA-II (%)

9.9 ± 1.5

9.4 ± 1.4

0.141

 HDL apoE (%)

0.5 ± 0.4

0.6 ± 0.2

0.518

 HDL apoC-III (%)

1.7 ± 0.6

1.7 ± 0.6

0.703

  1. Italic values indicate significance of p value (p < 0.05)
  2. * Indicates non-parametric values