| Normal GCT NGT | Abnormal GCT NGT | GIGT | GDM | P |
---|---|---|---|---|---|
(n = 76) | (n = 99) | (n = 59) | (n = 105) | ||
In pregnancy | |||||
 Age (years) | 35 ± 4 | 35 ± 4 | 34 ± 4 | 35 ± 4 | 0.71 |
 Ethnicity | 0.39 | ||||
  White (%) | 75.0 | 74.7 | 67.8 | 65.8 |  |
  Asian (%) | 6.6 | 9.1 | 11.9 | 17.1 |  |
  Other (%) | 18.4 | 16.2 | 20.3 | 17.1 |  |
 Family history of T2DM (%) | 54.0 | 59.6 | 64.4 | 64.8 | 0.46 |
 Fasting glucose on OGTT (mmol/L) | 4.3 ± 0.4 | 4.4 ± 0.3 | 4.6 ± 0.5 | 4.9 ± 0.7 | < 0.0001 |
 1-h glucose on OGTT (mmol/L) | 7.7 ± 1.2 | 8.4 ± 1.3 | 10.2 ± 1.3 | 11.3 ± 1.6 | < 0.0001 |
 2-h glucose on OGTT (mmol/L) | 6.7 ± 1.1 | 7.4 ± 1.0 | 8.4 ± 1.1 | 10.4 ± 1.5 | < 0.0001 |
 3-h glucose on OGTT (mmol/L) | 5.9 ± 1.2 | 5.8 ± 1.3 | 7.2 ± 1.3 | 8.1 ± 1.7 | < 0.0001 |
At 1-year postpartum | |||||
 Months breastfeeding (months) | 11 (6–12) | 10 (6–12) | 9 (4–12) | 10 (3–12) | 0.36 |
 BMI (kg/m2) | 24.4 (21.5–28.4) | 23.6 (21.8–27.8) | 25.4 (23.1–30.1) | 25.4 (22.5–29.4) | 0.12 |
 Waist circumference (cm) | 87 ± 12 | 85 ± 11 | 89 ± 13 | 89 ± 14 | 0.05 |
 Fasting glucose on OGTT (mmol/L) | 4.6 ± 0.3 | 4.6 ± 0.4 | 4.9 ± 0.6 | 4.9 ± 0.5 | < 0.0001 |
 2-h glucose on OGTT (mmol/L) | 5.3 ± 1.2 | 6.1 ± 1.5 | 6.4 ± 1.8 | 7.0 ± 1.9 | < 0.0001 |
 Current glucose tolerance status | < 0.0001 | ||||
  Normal (%) | 97.2 | 87.4 | 77.8 | 69.7 |  |
  Pre-diabetes/diabetes (%) | 2.8 | 12.6 | 22.2 | 30.3 |  |
 Adiponectin (μg/mL) | 10.0 ± 4.0 | 9.8 ± 3.9 | 8.2 ± 3.1 | 8.5 ± 2.9 | 0.002 |
 Chemerin (ng/mL) | 55.8 ± 12.7 | 55.3 ± 14.8 | 58.6 ± 13.9 | 54.8 ± 16.0 | 0.48 |
 RBP-4 (mg/L) | 35.8 ± 14.8 | 37.5 ± 13.3 | 34.9 ± 10.3 | 35.3 ± 9.9 | 0.56 |
 CRP (mg/L) | 1.2 (0.6–3.7) | 1.0 (0.5–2.9) | 1.3 (0.6–2.7) | 1.1 (0.7–3.1) | 0.92 |
 PAI-1 (pg/mL) | 7354 (6964–7683) | 7308 (6914–7667) | 7114 (6558–7612) | 7175 (6667–7540) | 0.09 |